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image: Mini Brains Model Autism

Mini Brains Model Autism

By | July 16, 2015

Patient-derived organoids reveal autism spectrum disorder–associated anomalies.

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image: Tracing Ebola’s Evolution

Tracing Ebola’s Evolution

By | June 18, 2015

Two independent teams examine the migration and evolution of the virus throughout the ongoing outbreak in West Africa.

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image: Cancer-Driving Mutations Common in Normal Skin Cells

Cancer-Driving Mutations Common in Normal Skin Cells

By | May 21, 2015

A deep-sequencing analysis reveals that non-malignant skin cells harbor many more cancer-driving mutations than previously expected. 

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Researchers develop a CRISPR-based, two-phage system that sensitizes resistant bacteria to antibiotics and selectively kills any remaining drug-resistant bugs. 

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image: Personalized Devices Predict Cancer Drug Response

Personalized Devices Predict Cancer Drug Response

By | April 22, 2015

Two teams have developed tumor-implantable drug delivery devices to study real-time responses to multiple therapies in cancer patients.

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image: Cancer Sequencing Controls

Cancer Sequencing Controls

By | April 15, 2015

Comparing a patient’s tumor DNA sequence with that of her normal tissue can improve researchers’ identification of disease-associated mutations.

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image: Clam Cancer Rips Along Atlantic Coast

Clam Cancer Rips Along Atlantic Coast

By | April 9, 2015

A leukemia that’s killing far-flung populations of softshell clams may be contagious. 

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image: Insulin Interference Triggers Cancer-Linked Cachexia

Insulin Interference Triggers Cancer-Linked Cachexia

By | April 6, 2015

A tumor-secreted protein interferes with insulin signaling to cause cancer-linked muscle wasting in fruit flies. 

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image: Personalized Cancer Vaccines

Personalized Cancer Vaccines

By | April 2, 2015

A dendritic cell vaccine targeting melanoma patients’ tumor-specific mutations can activate a broad range of cancer-fighting T cells. 

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image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.

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