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tag stem cell trials ecology stem cells genetics genomics

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Genotoxic Effects of Base and Prime Editing
Kamal Nahas, PhD | Jan 12, 2024 | 5 min read
A risk-benefit analysis of gene editing tools in stem cells revealed that base and prime editing carry vulnerabilities similar to those of CRISPR-Cas9, but at a reduced rate. 
Stem Cell Trial for Eye Disease Commences
Jef Akst | Sep 12, 2014 | 2 min read
Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.
A Master Regulator of Gene Expression
Mariella Bodemeier Loayza Careaga, PhD | Jan 31, 2024 | 4 min read
A CRISPR-based screening platform helped scientists identify a transcription factor that makes CAR T cells better at killing cancer cells. 
Patched-up human stem cells
Elie Dolgin | May 30, 2009 | 3 min read
For the first time, researchers have combined gene therapy and cellular reprogramming technologies in human cells to correct a genetic defect. After taking skin and hair cells from patients with a rare genetic disorder and fixing the aberrant mutation, the investigators successfully reprogrammed the cells to an embryonic-like state and then turned them into the very cell types that usually go awry, according to a linkurl:study;http://www.nature.com/nature/journal/vaop/ncurrent/abs/nature08129.ht
Not All Stem Cells Created Equal
Anna Azvolinsky | Jul 2, 2014 | 4 min read
Compared to induced pluripotent stem cells generated from somatic cells, stem cells created by nuclear transfer appear to be closer to the genetic state of embryonic cells.
Synthego Launches High Throughput Induced Pluripotent Stem Cell Genome Engineering
Synthego | Oct 29, 2019 | 2 min read
National Institutes of Health awards contract for CRISPR-based disease modeling in iPS cell lines associated with Alzheimer’s, Stem cell pioneer Bill Skarnes joins advisory board
Embryonic Stem Cells Work
Maria Anderson | Jun 20, 2004 | 6 min read
HALF A MIND:©2002, The National Academy of SciencesLesioned brains 16 weeks after embryonic stem cell transplant stain positive for tyrosine hydroxylase (TH: green), dopamine transporter (DAT: red), and aromatic amino acid decar-boxylase (AADC: blue) in an overlaid image. Bar equals 25 μm.Since drawing the attention of scientists, ethicists, and policymakers, stem cells have not lost their place as one of the most promising yet controversial scientific discoveries of the 20th century.
Nerve cell labelled with different colours
Psychedelics Slip Past Cell Membranes When Treating Depression
Alejandra Manjarrez, PhD | Feb 24, 2023 | 4 min read
The antidepressant properties of hallucinogenic drugs may stem from their ability to bind to intracellular serotonin receptors, a study suggests.
Stem cell therapy triggers tumor
Tia Ghose | Feb 17, 2009 | 3 min read
A neural stem cell transplant from fetal cells performed in Russia led to a brain tumor in a teenage boy, researchers in this week's PLoS Medicine report, raising concerns about the safety of neural stem cells treatments. MRI of brain lesion, courtesy of PLoS MedicineThe researchers confirmed that the cancer originated from the donor tissue, not the boy's own cells. This is the first report of cancer following fetal neural stem cell transplant. However, outside experts raised concerns about th

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