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Combined transcription and genome data from multiple tissues in hundreds of human donors reveal links between genotype and gene expression across the body.

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Mice receiving the treatment produced their own monoclonal antibodies and survived infection with the life-threatening pathogen Pseudomonas aeruginosa.

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image: Giants of Circadian Biology Win Nobel Prize

Giants of Circadian Biology Win Nobel Prize

By | October 2, 2017

The award in Physiology or Medicine goes to chronobiologists Jeffrey Hall, Michael Rosbash, and Michael Young.

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image: Booger Bacteria’s Sweet Immune Suppression

Booger Bacteria’s Sweet Immune Suppression

By | September 6, 2017

Sweet taste receptor-activating molecules produced by sinus microbes suppress the local innate immune system in humans.

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image: A Bacterial Messenger Molecule Extends Healthspan

A Bacterial Messenger Molecule Extends Healthspan

By | August 28, 2017

E. coli that make indoles protect older worms, flies, and mice from frailty. 

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image: Vitamin C Depletion Accelerates Leukemia in Mice

Vitamin C Depletion Accelerates Leukemia in Mice

By | August 21, 2017

High levels of vitamin C absorbed by blood-forming stem cells are important for their normal development. 

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image: Gordon Awandare: Ghana’s Homecoming King

Gordon Awandare: Ghana’s Homecoming King

By | August 21, 2017

The infectious disease scientist spent seven years in the U.S. before returning home to establish a thriving center for research and help lead the fight against malaria.

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image: Dengue Infection Impairs Immune Defense Against Zika

Dengue Infection Impairs Immune Defense Against Zika

By | August 18, 2017

A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.

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image: Vitamin C Blocks Leukemia Progression in Mice

Vitamin C Blocks Leukemia Progression in Mice

By | August 17, 2017

High-dose vitamin C injections reverse the effects of a leukemia-promoting genetic deficiency.

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image: The Cancer Genes Needed for Immunotherapy Response

The Cancer Genes Needed for Immunotherapy Response

By | August 7, 2017

Using a large CRISPR-based screen, researchers find possible genetic culprits for patients not having success with immune checkpoint inhibitors.  

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