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image: Trisomy 21 Effects Seen Genome-wide

Trisomy 21 Effects Seen Genome-wide

By | April 16, 2014

The extra chromosome behind Down’s syndrome can impact transcriptional regulation beyond chromosome 21, a study finds.

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image: Key Osmotic Channel Protein Identified

Key Osmotic Channel Protein Identified

By | April 10, 2014

A little-studied protein appears to be a critical part of the perplexing channel that prevents cells from bursting.

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image: Obesity Complicates Colorectal Cancer

Obesity Complicates Colorectal Cancer

By | April 9, 2014

Study finds that prediagnosis obesity is predictive of poor prognosis, even among patients who have a molecular marker associated with better disease outcome.

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People who report having enjoyed amphetamine are more likely to have gene variants associated with protection against attention deficit-hyperactivity disorder and schizophrenia, a study shows.

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image: An Ancient Evolutionary Advantage?

An Ancient Evolutionary Advantage?

By | April 1, 2014

Shared sequences within the brain lipid-metabolism pathway between Neanderthals and modern Europeans highlight questions about how these genetic similarities arose.

3 Comments

image: Synthetic Yeast Chromosome

Synthetic Yeast Chromosome

By | March 27, 2014

A heavily edited version of yeast shows just how flexible eukaryotic chromosomes can be.

3 Comments

image: Enhancer and Promoter Atlases

Enhancer and Promoter Atlases

By | March 26, 2014

Consortium annotates the human genome with cell type-specific information about transcription start sites, active enhancers, and their expression throughout the body.

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image: Origins of Lactase Persistence in Africa

Origins of Lactase Persistence in Africa

By | March 13, 2014

Large-scale sequencing effort confirms several mutations that confer lactase persistence in Africans, while haplotype analysis sheds light on the trait’s origins.

3 Comments

image: Whole-Genome Growing Pains

Whole-Genome Growing Pains

By | March 11, 2014

Small study suggests that whole-genome sequencing faces several hurdles before it can be used routinely in the clinic.

3 Comments

A butterfly’s varied disguises are controlled by variants of a single gene, partially confirming—and refuting—a decades-old hypothesis.

8 Comments

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