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image: Blood Stem Cells Grown in the Lab

Blood Stem Cells Grown in the Lab

By | May 17, 2017

Researchers identify transcription factors and environmental conditions necessary to reprogram human and mouse cells into cells that function like hematopoietic stem cells.

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image: Stem Cell Trial Data Mostly Go Unpublished

Stem Cell Trial Data Mostly Go Unpublished

By | May 5, 2017

Less than half of completed stem cell studies in humans are published in peer-reviewed journals, according to an analysis of regenerative medicine trials. 

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By implanting patient- or rodent-derived mini-guts into mice, scientists can rapidly create more-accurate murine models of the disease

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image: Developing Brains in Dishes

Developing Brains in Dishes

By | April 26, 2017

Two studies report methods to mimic human fetal brain development using neurons derived from human induced pluripotent stem cells that form 3-D, brain-like structures. 

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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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image: Suicide Switch for Transplanted Stem Cells

Suicide Switch for Transplanted Stem Cells

By | March 2, 2017

Researchers use an inducible gene to limit tumor growth from human iPSCs transplanted into mice.

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image: Abundant Sequence Errors in Public Databases

Abundant Sequence Errors in Public Databases

By | February 16, 2017

A new algorithm reveals hoards of preparation-induced DNA mutations in publicly available human sequences.

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image: Toward Killing Cancer with Bacteria

Toward Killing Cancer with Bacteria

By | February 8, 2017

Researchers employ an engineered microbe to destroy tumor cells in mice.

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image: Non-Chromosomal DNA Drives Tumor Evolution

Non-Chromosomal DNA Drives Tumor Evolution

By | February 8, 2017

Researchers discover that short pieces of DNA harboring oncogenes are relatively widespread in cancer.

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A cell phone–based microscope can identify mutations in tumor tissue and image products of DNA sequencing reactions.

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