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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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image: Abundant Sequence Errors in Public Databases

Abundant Sequence Errors in Public Databases

By | February 16, 2017

A new algorithm reveals hoards of preparation-induced DNA mutations in publicly available human sequences.

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image: Toward Killing Cancer with Bacteria

Toward Killing Cancer with Bacteria

By | February 8, 2017

Researchers employ an engineered microbe to destroy tumor cells in mice.

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image: Non-Chromosomal DNA Drives Tumor Evolution

Non-Chromosomal DNA Drives Tumor Evolution

By | February 8, 2017

Researchers discover that short pieces of DNA harboring oncogenes are relatively widespread in cancer.

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A cell phone–based microscope can identify mutations in tumor tissue and image products of DNA sequencing reactions.

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image: As the Brain Ages, Glial-Cell Gene Expression Changes Most

As the Brain Ages, Glial-Cell Gene Expression Changes Most

By | January 10, 2017

Researchers describe how gene expression in different human brain regions is altered with age.

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image: Speaking of Science: 2016

Speaking of Science: 2016

By | December 19, 2016

Selected quotes from an eventful year

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image: Gut Microbes Linked to Neurodegenerative Disease

Gut Microbes Linked to Neurodegenerative Disease

By | December 1, 2016

Bacteria in the intestine influence motor dysfunction and neuroinflammation in a mouse model of Parkinson’s disease.

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image: Smoking-Linked Cancer Mutations Mapped

Smoking-Linked Cancer Mutations Mapped

By | November 3, 2016

Scientists produce a detailed genomic map of mutations and epigenetic changes associated with smoking tobacco across 17 tumor types. 

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image: Nixing NETs to Prevent Metastasis

Nixing NETs to Prevent Metastasis

By | October 19, 2016

Researchers discover that neutrophil extracellular traps help cancers spread, and design enzyme-loaded nanoparticles to destroy them.

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