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“Rogue” Protein Could Contribute to Humans’ High Cancer Rates
“Rogue” Protein Could Contribute to Humans’ High Cancer Rates
A mutant protein called Siglec-XII may promote carcinoma progression in humans, but inactivation of its gene seems to avoid the problem, according to a study.
“Rogue” Protein Could Contribute to Humans’ High Cancer Rates
“Rogue” Protein Could Contribute to Humans’ High Cancer Rates

A mutant protein called Siglec-XII may promote carcinoma progression in humans, but inactivation of its gene seems to avoid the problem, according to a study.

A mutant protein called Siglec-XII may promote carcinoma progression in humans, but inactivation of its gene seems to avoid the problem, according to a study.

cell & molecular biology, evolutionary biology

model organism, zebrafish, sponge, cell &molecular biology, genetics & genomics, enhancer, transcription, non-coding DNA, gene regulation, evolution
Regulators of Gene Activity in Animals Are Deeply Conserved
Amanda Heidt | Nov 6, 2020 | 5 min read
Enhancers, short regions of DNA that direct gene expression, of species separated by 700 million years of evolution worked interchangeably, according to a new study.
How a Centipede Survives its Own Species’ Venom
Shawna Williams | Nov 1, 2020 | 2 min read
The same toxin targets different receptors in prey and conspecifics to deliver either a lethal or non-lethal blow.
shinkai submersible
Elusive Asgard Archaea Finally Cultured in Lab
Nicoletta Lanese | Aug 12, 2019 | 3 min read
The 12-year-long endeavor reveals Prometheoarchaeum as a tentacled cell, living in a symbiotic relationship with methane-producing microbes.
Infographic: Resurrecting Ancient Proteins
Amber Dance | Jul 1, 2018 | 2 min read

Learn the basic steps researchers take when reconstructing proteins from the past and how these biomolecules can inform engineering projects.

Scientists Bring Ancient Proteins Back to Life
Amber Dance | Jul 1, 2018 | 10+ min read
Researchers are resurrecting proteins from millions of years ago to understand evolution and lay the groundwork for bioengineering custom molecules.
Week in Review: October 17–21
Jef Akst | Oct 20, 2016 | 2 min read
Report finds that pathologist involved in anonymous defamation case committed multiple acts of misconduct; growing eggs from stem cells; neutrophils’ role in metastasis; convergent evolution in birds
Week in Review: February 22–26
Jef Akst | Feb 26, 2016 | 3 min read
Questions about how E. coli evolves; spermatids in a dish; fighting bacteria with virus-like molecule; what drives metastasis; antibodies fight Ebola in monkeys
How Multicellularity Arose
Jef Akst | Jan 11, 2016 | 1 min read
Researchers identify a molecule that may have been key to the surprisingly common transition from single-celled ancestors to today’s complex, multicellular organisms. 
Week in Review: July 14–18
Tracy Vence | Jul 18, 2014 | 3 min read
Converting heart muscle to pacemaker cells in pigs; alternative splicing and the human proteome; questioning a reported yogurt mold-illness link; H. pylori swiftly find mouse stomach injuries
Week in Review: May 26–30
Tracy Vence | May 30, 2014 | 4 min read
Human proteome cataloged; island-separated crickets evolved silence; molecule shows promise for combatting coronaviruses; study replication etiquette; another call for STAP retraction
Week in Review: January 27–31
Tracy Vence | Jan 31, 2014 | 3 min read
Stimulus-triggered pluripotency; antioxidants speed lung tumor growth; the importance of seminal vesicles; how a plant pathogen jumps hosts
Week in Review: January 20–24
Tracy Vence | Jan 23, 2014 | 3 min read
Mistimed sleep disrupts human transcriptome; canine tumor genome; de novo Drosophila genes; UVA light lowers blood pressure; aquatic microfauna fight frog-killing fungus
Top Scientists of 2013
Tracy Vence | Dec 24, 2013 | 3 min read
The Scientist commemorates prize-winning life scientists and remembers notable researchers who died this year.
Week in Review: December 9–13
Tracy Vence | Dec 13, 2013 | 3 min read
Animal family tree rearranged; how E. coli evades the immune system; pharmacological chaperones and misfolded proteins
Week in Review: December 2–6
Tracy Vence | Dec 6, 2013 | 3 min read
Oldest hominin DNA sequence; visualizing dyslexia; testing CRISPR; cancer and autoimmunity
Week in Review: November 18–22
Tracy Vence | Nov 22, 2013 | 4 min read
Chilly mice develop more tumors; gut bacteria aid cancer treatment; two Y chromosome genes sufficient for assisted reproduction; HIV’s “invisibility cloak”
Evolving Pain Resistance
Jef Akst | Oct 24, 2013 | 4 min read
Grasshopper mice harbor mutations in a pain-transmitting sodium channel that allow them to prey on highly toxic bark scorpions.
A Scientist Emerges
Jef Akst | Aug 1, 2012 | 3 min read
At age 16, Alexandra Sourakov has her first scientific publication, on the foraging behavior of butterflies.
Live Slow, Die Old
Ed Yong | May 17, 2012 | 3 min read
Ancient bacteria living in deep-sea sediments are alive—but with metabolisms so slow that it’s hard to tell.
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