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image: As the Brain Ages, Glial-Cell Gene Expression Changes Most

As the Brain Ages, Glial-Cell Gene Expression Changes Most

By | January 10, 2017

Researchers describe how gene expression in different human brain regions is altered with age.

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image: Induced Pluripotent Stem Cells Show Signs of Donor Age

Induced Pluripotent Stem Cells Show Signs of Donor Age

By | December 12, 2016

iPSCs created through the reprogramming of human somatic cells retain genomic marks of the donor’s age.

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image: Controlled Splicing Extends Life Span in Roundworms

Controlled Splicing Extends Life Span in Roundworms

By | December 7, 2016

Increasing the expression of an RNA splicing factor mimics dietary restriction, prolonging life in nematodes. 

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image: Gut Microbes Linked to Neurodegenerative Disease

Gut Microbes Linked to Neurodegenerative Disease

By | December 1, 2016

Bacteria in the intestine influence motor dysfunction and neuroinflammation in a mouse model of Parkinson’s disease.

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image: Next Generation: Super-Fast Tracking of Single Molecules

Next Generation: Super-Fast Tracking of Single Molecules

By | November 23, 2016

A clever twist on a super-resolution microscopy technique improves the temporal resolution of single-molecule tracking. 

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image: Molecular Machinists Win Nobel

Molecular Machinists Win Nobel

By | October 5, 2016

Chemists Jean-Pierre Sauvage, J. Fraser Stoddart, and Bernard Feringa are honored for their design and synthesis of molecular machines.

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image: Circadian-Controlled Thirst

Circadian-Controlled Thirst

By | September 28, 2016

Scientists determine how the brain’s central clock regulates drinking prior to sleep in rodents.

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Matching the immunological characteristics of donor retinal cells to those of the recipient can reduce the chance of rejection.

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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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