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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR/Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not in fact necessary for cancer cell survival.

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image: Abundant Sequence Errors in Public Databases

Abundant Sequence Errors in Public Databases

By | February 16, 2017

A new algorithm reveals hoards of preparation-induced DNA mutations in publicly available human sequences.

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image: Toward Killing Cancer with Bacteria

Toward Killing Cancer with Bacteria

By | February 8, 2017

Researchers employ an engineered microbe to destroy tumor cells in mice.

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image: Non-Chromosomal DNA Drives Tumor Evolution

Non-Chromosomal DNA Drives Tumor Evolution

By | February 8, 2017

Researchers discover that short pieces of DNA harboring oncogenes are relatively widespread in cancer.

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A cell phone–based microscope can identify mutations in tumor tissue and image products of DNA sequencing reactions.

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image: Natural Selection Kept Neanderthal DNA in Modern Humans

Natural Selection Kept Neanderthal DNA in Modern Humans

By | December 29, 2016

Interbreeding with Neanderthals appears to have reintroduced genetic sequences related to innate immunity that had been lost as humans migrated out of Africa. 

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image: Speaking of Science: 2016

Speaking of Science: 2016

By | December 19, 2016

Selected quotes from an eventful year

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image: Smoking-Linked Cancer Mutations Mapped

Smoking-Linked Cancer Mutations Mapped

By | November 3, 2016

Scientists produce a detailed genomic map of mutations and epigenetic changes associated with smoking tobacco across 17 tumor types. 

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image: How These Rodents Got Their Stripes

How These Rodents Got Their Stripes

By | November 2, 2016

The African striped mouse and the chipmunk develop dorsal stripes through a newly identified mechanism of coat color variation.

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image: Many Evolutionary Paths Lead to Same Bird Trait

Many Evolutionary Paths Lead to Same Bird Trait

By | October 20, 2016

Diverse genetic changes lead to remarkably similar hemoglobin adaptations of diverse bird species, a study finds. 

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