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image: Evolutionary Rewiring

Evolutionary Rewiring

By | February 26, 2015

Strong selective pressure can lead to rapid and reproducible evolution in bacteria.

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image: Stem Cells Phone Home

Stem Cells Phone Home

By | February 26, 2015

A screen of 9,000 small molecules identifies a treatment that improves the targeting of mesenchymal stem cells to sites of damaged tissue.

1 Comment

image: Stemming Genetic Changes in Cultured Cells

Stemming Genetic Changes in Cultured Cells

By | February 25, 2015

Researchers report an association between culture conditions and genetic changes in stem cells over time.

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image: Exploring the Epigenome

Exploring the Epigenome

By | February 18, 2015

A National Institutes of Health-funded consortium publishes 111 reference maps of DNA and histone marks.

2 Comments

image: Long-Lived Immunotherapy Stem Cells

Long-Lived Immunotherapy Stem Cells

By | February 4, 2015

Genetically modified T memory stem cells persist in patients for more than 10 years, and can differentiate into a variety of T cell types.

1 Comment

image: How Transposons Shaped Pregnancy

How Transposons Shaped Pregnancy

By | January 29, 2015

A mass migration of mobile regulatory elements increased the expression of thousands of genes in the uterus during the evolution of pregnancy.

1 Comment

image: Tracking Tuberculosis Over Time

Tracking Tuberculosis Over Time

By | January 19, 2015

Genomic analysis of a multidrug-resistant lineage pinpoints historical correlations with human events.

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image: Stem Cell Divisions Help Explain Cancer Risk

Stem Cell Divisions Help Explain Cancer Risk

By | January 1, 2015

An analysis of 31 tissues finds that random mutations acquired during stem cell divisions correlate with lifetime cancer risk—more so than heritable mutations and environmental factors combined.  

7 Comments

image: Unraveling H7N9’s History

Unraveling H7N9’s History

By | December 30, 2014

An analysis of stored samples shows that H7N9 precursor H9N2, a virus widespread in chickens, has shown increased fitness in recent years.

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image: Science Setbacks: 2014

Science Setbacks: 2014

By | December 25, 2014

This year in life science was marked by paltry federal funding increases, revelations of sequence contamination, and onerous regulations.

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