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image: Vitamin C Blocks Leukemia Progression in Mice

Vitamin C Blocks Leukemia Progression in Mice

By | August 17, 2017

High-dose vitamin C injections reverse the effects of a leukemia-promoting genetic deficiency.

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image: The Cancer Genes Needed for Immunotherapy Response

The Cancer Genes Needed for Immunotherapy Response

By | August 7, 2017

Using a large CRISPR-based screen, researchers find possible genetic culprits for patients not having success with immune checkpoint inhibitors.  

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Two freely available databases include data on hundreds of human cancer cell lines. 

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image: Stem Cells in the Hypothalamus Slow Aging in Mice

Stem Cells in the Hypothalamus Slow Aging in Mice

By | July 26, 2017

Once implanted into animals’ brains, neural stem cells that secrete microRNA-containing vesicles seem to contribute to an anti-aging effect.

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image: Transgenic Mouse Illuminates Melanoma Metastasis

Transgenic Mouse Illuminates Melanoma Metastasis

By | June 28, 2017

Glowing cells mark the routes of tumor spread by way of newly formed lymph vessels. 

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An analysis of human cancer genome projects uncovers a counterintuitive loss of ribosomal gene copies.

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A study suggests that “chief” cells in the stomach act as reserve stem cells that are activated by tissue damage and may be the long-sought source of gastric cancer.

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image: Blood Stem Cells Grown in the Lab

Blood Stem Cells Grown in the Lab

By | May 17, 2017

Researchers identify transcription factors and environmental conditions necessary to reprogram human and mouse cells into cells that function like hematopoietic stem cells.

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image: Stem Cell Trial Data Mostly Go Unpublished

Stem Cell Trial Data Mostly Go Unpublished

By | May 5, 2017

Less than half of completed stem cell studies in humans are published in peer-reviewed journals, according to an analysis of regenerative medicine trials. 

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By implanting patient- or rodent-derived mini-guts into mice, scientists can rapidly create more-accurate murine models of the disease

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