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image: Circular Chromosomes Straightened

Circular Chromosomes Straightened

By | November 6, 2014

A newly described method linearizes circular chromosomes in yeast and caps them with telomeres to mimic natural chromosomes.

1 Comment

image: Modified Yeast Tolerate Alcohol, Heat

Modified Yeast Tolerate Alcohol, Heat

By | October 2, 2014

Simple changes help yeast thrive in the presence of their own harmful byproducts and could boost biofuel production.

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image: Epigenetics of Trained Innate Immunity

Epigenetics of Trained Innate Immunity

By | September 25, 2014

Documenting the epigenetic landscape of human innate immune cells reveals pathways essential for training macrophages.

2 Comments

image: Toward Yeast–Based Opioid Production

Toward Yeast–Based Opioid Production

By | August 24, 2014

Synthetic biologists introduce bacterial and poppy plant genes into yeast to manufacture morphine.

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image: Protein Clumps Spread Inflammation

Protein Clumps Spread Inflammation

By | June 22, 2014

ASC specks—protein aggregations that drive inflammation—are released from dying immune cells, expanding the reach of a defense response.

1 Comment

image: Ancient Apoptosis

Ancient Apoptosis

By | June 9, 2014

Humans and coral share a cell-death pathway that has been conserved between them for more than half a billion years.

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image: Synthetic Yeast Chromosome

Synthetic Yeast Chromosome

By | March 27, 2014

A heavily edited version of yeast shows just how flexible eukaryotic chromosomes can be.

3 Comments

image: Vitamin A’s Influence on Immunity

Vitamin A’s Influence on Immunity

By | March 19, 2014

Exposure to vitamin A in the womb influences immune system development and lifelong ability to fight infections, a mouse study shows. 

1 Comment

image: Immune Response Promotes Infection

Immune Response Promotes Infection

By | February 6, 2014

Salmonella enterica can exploit a standard immune response in mice to promote its own growth.

2 Comments

image: Pruning Synapses Improves Brain Connections

Pruning Synapses Improves Brain Connections

By | February 2, 2014

Without microglia to pluck off unwanted synapses in early life, mouse brains develop with weaker connections, leading to altered social behavior.

1 Comment

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