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image: Dengue Infection Impairs Immune Defense Against Zika

Dengue Infection Impairs Immune Defense Against Zika

By | August 18, 2017

A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.

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image: T Cells That Drive Toxic Shock in Mice Identified

T Cells That Drive Toxic Shock in Mice Identified

By | June 20, 2017

Overzealous activity by mucosa-associated invariant T (MAIT) cells in response to bacterial toxins can lead to illness instead of stopping it.

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Research shows that human immunity develops much earlier than previously thought, but functions differently in adults.

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image: Viral Trigger for Celiac Disease?

Viral Trigger for Celiac Disease?

By | April 6, 2017

A common, seemingly benign human virus can trigger an immune response that leads to celiac disease in a mouse model, researchers show. 

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image: Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

By | March 30, 2017

Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.

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image: Five More Synthetic Yeast Chromosomes Completed

Five More Synthetic Yeast Chromosomes Completed

By | March 9, 2017

Members of the Synthetic Yeast Genome Project have synthesized five additional yeast chromosomes from scratch. 

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image: Duplicated Genes May Reduce Resilience in Yeast

Duplicated Genes May Reduce Resilience in Yeast

By | February 14, 2017

Researchers find that some duplicated yeast genes develop dependency—the loss of one copy leads to the failure of the other.

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image: Unique Antibodies Open Path Toward New HIV Vaccines

Unique Antibodies Open Path Toward New HIV Vaccines

By | January 27, 2017

A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and treatments that target multiple strains of the virus.

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image: Naive T Cells Find Homes in Lymphoid Tissue

Naive T Cells Find Homes in Lymphoid Tissue

By | December 2, 2016

The human lymph nodes and spleen maintain unique, compartmentalized sets of naive T cells well into old age.

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image: Culprit for Antibody Blockade Identified

Culprit for Antibody Blockade Identified

By | October 21, 2016

Type I interferon organizes several immune mechanisms to suppress B cell responses to a chronic viral infection.

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