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image: CRISPR Corrects Duchenne-Causing Mutations

CRISPR Corrects Duchenne-Causing Mutations

By | April 12, 2017

Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.

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image: Viral Trigger for Celiac Disease?

Viral Trigger for Celiac Disease?

By | April 6, 2017

A common, seemingly benign human virus can trigger an immune response that leads to celiac disease in a mouse model, researchers show. 

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Octopus, cuttlefish, and squid extensively edit messenger RNAs in an evolutionarily conserved process. 

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image: Cross-Sample Sequencing Contamination Galore

Cross-Sample Sequencing Contamination Galore

By | April 5, 2017

Scientists conducting a large-scale, comparative transcriptomics project have inadvertently highlighted widespread contamination in sequencing data.

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image: CRISPR Screen Detects Functional Gene Regulation

CRISPR Screen Detects Functional Gene Regulation

By | April 3, 2017

A CRISPR-Cas9–based method probes the regulatory roles of noncoding DNA sequences.

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image: Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

By | March 30, 2017

Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.

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image: Should Healthy People Have Their Exomes Sequenced?

Should Healthy People Have Their Exomes Sequenced?

By | March 24, 2017

With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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Mitochondrial DNA polymerase is necessary for the destruction of paternal mtDNA in fruit fly sperm, scientists show.

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Proteins with unstable 3-D structures help the microscopic animals withstand drying.

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image: Five More Synthetic Yeast Chromosomes Completed

Five More Synthetic Yeast Chromosomes Completed

By | March 9, 2017

Members of the Synthetic Yeast Genome Project have synthesized five additional yeast chromosomes from scratch. 

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