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neuroscience, disease & medicine

The Biology of Suicidal Thoughts in PTSD Patients
Catherine Offord | Sep 1, 2019 | 2 min read
Researchers link levels of a receptor in the brain to suicidal ideation in people with post-traumatic stress disorder.
human macrophage
Image of the Day: Alzheimer’s Genes
Nicoletta Lanese | Aug 19, 2019 | 1 min read
Mutations within the MS4A gene cluster have been linked to changes in protein levels that affect disease risk.
schwann cells
Special Schwann Cells in Mice Play Unsung Role in Pain
Nicoletta Lanese | Aug 16, 2019 | 2 min read
The glia seem to make up part of a newly described sensory organ, the discoverers suggest.
sei proteins help protect flies from heat-induced seizures
Image of the Day: Seizure Proteins
Nicoletta Lanese | Aug 14, 2019 | 1 min read
The sei ion channel in fruit flies keeps their neuronal excitability in check.
smartphone controlled device implanted in mouse brain
Image of the Day: Smartphone-Controlled Brains
Nicoletta Lanese | Aug 7, 2019 | 1 min read
A device implanted into mice can modulate brain circuit activity over long periods of time.
LED flight simulator for mosquitos
Image of the Day: Mosquito Flight Simulator
Nicoletta Lanese | Jul 30, 2019 | 1 min read
Carbon dioxide pumped into a bright chamber mimics a breathing host for the pest to target.
Commensal Bacterium Reduces ALS Symptoms in Mice
Jef Akst | Jul 24, 2019 | 2 min read
Boosting the levels of Akkermansia muciniphila in mouse guts slowed the progression of an ALS-like disease, while two other microbiome members were associated with more severe symptoms.
Forced-Swim Test Criticized as Uninformative, Cruel
Catherine Offord | Jul 22, 2019 | 2 min read
Some researchers and animal rights groups are amplifying their opposition to an assay that measures how long a rodent tries to stay afloat.
prosthetic hand muscle signals signal move fingers amputee robotics 3d printed printing
Image of the Day: Second Hand
Chia-Yi Hou | Jul 10, 2019 | 1 min read
A 3-D printed prosthetic hand moves by reading the signals in forearm muscles.
c Caenorhabditis elegans neural map neuron pathway connections connectome
Biologists Create New Maps of Caenorhabditis elegans Neurons
Chia-Yi Hou | Jul 8, 2019 | 2 min read
The connectomes trace 385 neurons in the male worm and 302 neurons in the hermaphrodite worm.
Gut Microbes May Play a Role in Mental Health Disorders
Ashley Yeager | Jul 5, 2019 | 4 min read
The gut microbiome has been linked to depression, schizophrenia, and other neurological conditions, but it’s not yet clear whether the relationship is causal.
ted dawson alpha-synuclein parkinson's disease model gut vagus nerve dopamine johns hopkins school of medicine
Mouse Model Shows How Parkinson’s Disease Begins in the Gut
Emma Yasinski | Jun 26, 2019 | 3 min read
Johns Hopkins’s Ted Dawson discusses his lab’s demonstration that misfolded α-synuclein can move from the stomach to the brain and cause physical and cognitive symptoms.
cardiac heart catheter ablation atrial fibrillation s100b
A Common Atrial Fibrillation Procedure Is Aided by Damaging Neurons
Emma Yasinski | May 24, 2019 | 4 min read
Patients in a study of catheter ablation who showed signs of more injury to nerve cells and glia in the heart had fewer symptoms after the treatment.
Neural Cell Types Tied to Autism Identified in Single-Cell Study
Ruth Williams | May 16, 2019 | 3 min read
An RNA analysis of human brain cells reveals gene expression changes in cortical neurons and microglia linked to autism spectrum disorder (ASD).
Circulation and Cell Function Revived in Dead Pigs’ Brains
Chia-Yi Hou | Apr 17, 2019 | 3 min read
Researchers develop a system to deliver synthetic blood to isolated brains hours after death.
How the Brain Changes on Ketamine: A Live Animal Study
Ruth Williams | Apr 11, 2019 | 3 min read
The drug promotes and sustains brain cell connectivity in mice, reversing the effects of chronic stress.
oliver sacks book everything in its place
A Review of Everything in Its Place: First Loves and Last Tales
Bob Grant | Apr 1, 2019 | 3 min read
This posthumously published collection of essays by Oliver Sacks further cements the neurologist’s place in the pantheon of science writers.
More Evidence that Humans Do Appear to Create New Neurons in Old Age
Ashley Yeager | Mar 25, 2019 | 4 min read
Despite doubts last year about human adult neurogenesis, a study shows even 80-year-olds develop new cells in the hippocampus, but such growth is diminished in patients with Alzheimer’s disease.
Potent Weed Linked to Psychosis
Jef Akst | Mar 20, 2019 | 2 min read
Frequent use of high-strength cannabis may increase the risk of mental health problems, according to a large-scale epidemiological study.
Rapidly Flashing Lights and Sounds Reduces Alzheimer’s in Mice
Jef Akst | Mar 15, 2019 | 2 min read
Exposing mice to an hour of 40-hertz stimuli every day for a week reduced levels of amyloid-β plaques and tau protein, and improved cognition.
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