The Johns Hopkins University researcher bucked the prevailing idea that the body would not launch an immune response against its own tissues, and in doing so established an entirely new scientific discipline.
A B-cell receptor critical for the production of a subset of intestinal antibodies has been pinpointed, but the function of those antibodies remains unclear.
By revealing that animals could develop immune responses against their own tissues, the physician-scientist established an entirely new field of science.
The genetically modified bacteria spark an RNAi response in the parasite that leads to self-destruction—and perhaps a path to combatting colony collapse disorder.
Animal studies and a few small clinical trials show it’s possible to get commensal microbes to protect against bone loss, rather than contribute to it.