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image: Epigenetics of Trained Innate Immunity

Epigenetics of Trained Innate Immunity

By | September 25, 2014

Documenting the epigenetic landscape of human innate immune cells reveals pathways essential for training macrophages.

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image: Protein Clumps Spread Inflammation

Protein Clumps Spread Inflammation

By | June 22, 2014

ASC specks—protein aggregations that drive inflammation—are released from dying immune cells, expanding the reach of a defense response.

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image: Ancient Apoptosis

Ancient Apoptosis

By | June 9, 2014

Humans and coral share a cell-death pathway that has been conserved between them for more than half a billion years.

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image: Vitamin A’s Influence on Immunity

Vitamin A’s Influence on Immunity

By | March 19, 2014

Exposure to vitamin A in the womb influences immune system development and lifelong ability to fight infections, a mouse study shows. 

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image: Immune Response Promotes Infection

Immune Response Promotes Infection

By | February 6, 2014

Salmonella enterica can exploit a standard immune response in mice to promote its own growth.

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image: Pruning Synapses Improves Brain Connections

Pruning Synapses Improves Brain Connections

By | February 2, 2014

Without microglia to pluck off unwanted synapses in early life, mouse brains develop with weaker connections, leading to altered social behavior.

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image: How HIV Destroys Immune Cells

How HIV Destroys Immune Cells

By | December 19, 2013

During HIV infection, CD4 T cells in lymphoid tissues initiate a highly inflammatory form of cell death that helps cripple the immune system.  

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image: Dogs, Dust Microbes, and Allergies

Dogs, Dust Microbes, and Allergies

By | December 16, 2013

Dust-borne bacteria from houses with dogs can prevent allergies in mice by changing their gut microbes.

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image: Cancer and Immune Cells Merge

Cancer and Immune Cells Merge

By | December 16, 2013

Mouse colon cancer cells can fuse with macrophages, leading to changes in tumor growth.

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image: A Cancer Culprit in Autoimmunity

A Cancer Culprit in Autoimmunity

By | December 5, 2013

Scientists discover that cancer can drive the autoimmune disorder scleroderma.

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