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image: Stem Cell Divisions Help Explain Cancer Risk

Stem Cell Divisions Help Explain Cancer Risk

By | January 1, 2015

An analysis of 31 tissues finds that random mutations acquired during stem cell divisions correlate with lifetime cancer risk—more so than heritable mutations and environmental factors combined.  

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image: Focus on Sex

Focus on Sex

By | December 29, 2014

In 2014, new research findings and guidelines brought increased attention to biological differences between males and females.

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image: Vanishing Y Chromosomes

Vanishing Y Chromosomes

By | December 4, 2014

A new study reveals an association between smoking and rates of Y chromosome loss in blood cells, which may explain elevated cancer risk among male smokers.

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image: Illuminating the Interactome

Illuminating the Interactome

By | November 20, 2014

A massive screen yields the most comprehensive map of binary human protein interactions to date.

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image: Epigenetic Changes Can Cause Cancer

Epigenetic Changes Can Cause Cancer

By | July 25, 2014

A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model. 

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image: A Multi-Cancer Diagnostic?

A Multi-Cancer Diagnostic?

By | July 14, 2014

Researchers report an ability to detect several types of cancer in blood samples based on signatures of immune response, but some are skeptical about the utility of such a test.

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image: Targeted Brain Cancer Vaccine

Targeted Brain Cancer Vaccine

By | June 25, 2014

Mouse study demonstrates the ability of a cancer vaccine targeted against a specific oncogenic mutation to elicit a protective anti-tumor immune response. 

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Scientists generate tumor-targeting molecules that can be used for imaging and treatment.

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image: Making Sense of the Tumor Exome

Making Sense of the Tumor Exome

By | May 18, 2014

An algorithm can pick out biologically and clinically meaningful variants from whole-exome sequences of tumors.

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image: Obesity Complicates Colorectal Cancer

Obesity Complicates Colorectal Cancer

By | April 9, 2014

Study finds that prediagnosis obesity is predictive of poor prognosis, even among patients who have a molecular marker associated with better disease outcome.

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