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image: CRISPR Screen Detects Functional Gene Regulation

CRISPR Screen Detects Functional Gene Regulation

By | April 3, 2017

A CRISPR-Cas9–based method probes the regulatory roles of noncoding DNA sequences.

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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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image: Should Healthy People Have Their Exomes Sequenced?

Should Healthy People Have Their Exomes Sequenced?

By | March 24, 2017

With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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Mitochondrial DNA polymerase is necessary for the destruction of paternal mtDNA in fruit fly sperm, scientists show.

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Proteins with unstable 3-D structures help the microscopic animals withstand drying.

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image: Five More Synthetic Yeast Chromosomes Completed

Five More Synthetic Yeast Chromosomes Completed

By | March 9, 2017

Members of the Synthetic Yeast Genome Project have synthesized five additional yeast chromosomes from scratch. 

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image: How Bacteria Interfere with Insect Reproduction

How Bacteria Interfere with Insect Reproduction

By | February 28, 2017

Scientists identify the genes responsible for bacteria-controlled sterility in arthropods.

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image: An Aging-Related Effect on the Circadian Clock

An Aging-Related Effect on the Circadian Clock

By | February 21, 2017

Stress-related genes may be preferentially and rhythmically expressed as part of the circadian rhythms of older fruit flies, researchers report.  

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image: Abundant Sequence Errors in Public Databases

Abundant Sequence Errors in Public Databases

By | February 16, 2017

A new algorithm reveals hoards of preparation-induced DNA mutations in publicly available human sequences.

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image: Pardis Sabeti: An American Scientist Born in Iran

Pardis Sabeti: An American Scientist Born in Iran

By | February 9, 2017

When she entered the U.S. shortly before the Iranian revolution of 1979, the now 41-year-old geneticist was a refugee toddler. 

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