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image: Cancer Sequencing Controls

Cancer Sequencing Controls

By | April 15, 2015

Comparing a patient’s tumor DNA sequence with that of her normal tissue can improve researchers’ identification of disease-associated mutations.

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image: Clam Cancer Rips Along Atlantic Coast

Clam Cancer Rips Along Atlantic Coast

By | April 9, 2015

A leukemia that’s killing far-flung populations of softshell clams may be contagious. 

2 Comments

image: Insulin Interference Triggers Cancer-Linked Cachexia

Insulin Interference Triggers Cancer-Linked Cachexia

By | April 6, 2015

A tumor-secreted protein interferes with insulin signaling to cause cancer-linked muscle wasting in fruit flies. 

2 Comments

image: Personalized Cancer Vaccines

Personalized Cancer Vaccines

By | April 2, 2015

A dendritic cell vaccine targeting melanoma patients’ tumor-specific mutations can activate a broad range of cancer-fighting T cells. 

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image: Engineered Biomarkers Could ID Cancer Cells

Engineered Biomarkers Could ID Cancer Cells

By | February 23, 2015

Scientists develop synthetic blood-based biomarkers to amplify tumor signals in a mouse model.

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image: Exploring the Epigenome

Exploring the Epigenome

By | February 18, 2015

A National Institutes of Health-funded consortium publishes 111 reference maps of DNA and histone marks.

2 Comments

image: Culturing Changes Cells

Culturing Changes Cells

By | February 3, 2015

Within days of their transfer to a dish, a certain epigenetic mark vanishes from mouse cells.

2 Comments

image: Benefits of Missing MYC

Benefits of Missing MYC

By | January 22, 2015

Mice engineered to have just one copy of the gene Myc live longer, healthier lives than wild-type animals.

1 Comment

image: Stem Cell Divisions Help Explain Cancer Risk

Stem Cell Divisions Help Explain Cancer Risk

By | January 1, 2015

An analysis of 31 tissues finds that random mutations acquired during stem cell divisions correlate with lifetime cancer risk—more so than heritable mutations and environmental factors combined.  

7 Comments

image: Focus on Sex

Focus on Sex

By | December 29, 2014

In 2014, new research findings and guidelines brought increased attention to biological differences between males and females.

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