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image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.

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image: Evolutionary Rewiring

Evolutionary Rewiring

By | February 26, 2015

Strong selective pressure can lead to rapid and reproducible evolution in bacteria.

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image: Stem Cells Phone Home

Stem Cells Phone Home

By | February 26, 2015

A screen of 9,000 small molecules identifies a treatment that improves the targeting of mesenchymal stem cells to sites of damaged tissue.

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image: Stemming Genetic Changes in Cultured Cells

Stemming Genetic Changes in Cultured Cells

By | February 25, 2015

Researchers report an association between culture conditions and genetic changes in stem cells over time.

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image: The Dark Side of Melanin

The Dark Side of Melanin

By | February 19, 2015

Researchers uncover a previously unknown way UV light can act on melanin, spurring cancer-causing mutations hours after sun exposure.

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image: Exploring the Epigenome

Exploring the Epigenome

By | February 18, 2015

A National Institutes of Health-funded consortium publishes 111 reference maps of DNA and histone marks.

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image: Long-Lived Immunotherapy Stem Cells

Long-Lived Immunotherapy Stem Cells

By | February 4, 2015

Genetically modified T memory stem cells persist in patients for more than 10 years, and can differentiate into a variety of T cell types.

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image: Crystal Structure, Murky Function

Crystal Structure, Murky Function

By | January 29, 2015

Scientists have determined the crystal structures of bacterial translocator proteins, but their functions remain unclear.

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image: Human Proteome Mapped Again

Human Proteome Mapped Again

By | January 22, 2015

Researchers complete another interactive protein atlas, boosting the number of publicly available maps of human protein expression levels.

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image: Stem Cell Divisions Help Explain Cancer Risk

Stem Cell Divisions Help Explain Cancer Risk

By | January 1, 2015

An analysis of 31 tissues finds that random mutations acquired during stem cell divisions correlate with lifetime cancer risk—more so than heritable mutations and environmental factors combined.  

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