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image: Yeast-Based Opioid Production Completed

Yeast-Based Opioid Production Completed

By | August 13, 2015

Researchers fully engineer a biochemical pathway that turns a sugar into an opioid in Saccharomyces cerevisiae.


image: Mini Brains Model Autism

Mini Brains Model Autism

By | July 16, 2015

Patient-derived organoids reveal autism spectrum disorder–associated anomalies.


image: Tracing Ebola’s Evolution

Tracing Ebola’s Evolution

By | June 18, 2015

Two independent teams examine the migration and evolution of the virus throughout the ongoing outbreak in West Africa.


image: Human Genes Can Save Yeast

Human Genes Can Save Yeast

By | May 21, 2015

Replacing yeast genes with their human equivalents reveals functional conservation despite a billion years of divergent evolution.


Researchers develop a CRISPR-based, two-phage system that sensitizes resistant bacteria to antibiotics and selectively kills any remaining drug-resistant bugs. 


image: Cancer Sequencing Controls

Cancer Sequencing Controls

By | April 15, 2015

Comparing a patient’s tumor DNA sequence with that of her normal tissue can improve researchers’ identification of disease-associated mutations.

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image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.


image: T Cells of the Skin

T Cells of the Skin

By | March 18, 2015

A census of adaptive immune system components in human skin reveals a variety of resident and traveling memory T cells.

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image: The Dark Side of Melanin

The Dark Side of Melanin

By | February 19, 2015

Researchers uncover a previously unknown way UV light can act on melanin, spurring cancer-causing mutations hours after sun exposure.


image: Long-Lived Immunotherapy Stem Cells

Long-Lived Immunotherapy Stem Cells

By | February 4, 2015

Genetically modified T memory stem cells persist in patients for more than 10 years, and can differentiate into a variety of T cell types.

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