Running releases an enzyme that is associated with memory function in mice and humans.
July 14, 2000|
The function of an uncharacterized gene can sometimes be determined by mutating the gene and using a phenotypic assay But sometimes a convenient phenotype does not exist for a given cellular function. Hughes et al. suggest in the July 7 Cell that expression profiles can be used instead (Cell 2000, 102:109-126). Rather than measuring expression profiles as conditions change (e.g., at different points in the cell cycle, Hughes et al. keep the culture conditions constant and measure the profiles of