genetics & genomics, genetics, CRISPR

A biotech startup called Tessera Therapeutics has made a splash with its claims about the trademarked technology. Is the excitement justified?

Massive extrachromosomal elements named after the hive-minded cyborg villains in Star Trek may be the first of their kind.

The International Commission on the Clinical Use of Human Germline Genome Editing claims the technology is still too risky for therapeutic use.

Three studies identify unintended consequences of gene editing in human embryos, including large deletions and reshuffling of DNA.

The modification of three babies’ genes by He Jiankui drew widespread criticism from scientists.

In demonstrations in cell lines, the technique has a similar efficacy to CRISPR-Cas9, but fewer off-target effects.

The research, led by Russian biologist Denis Rebrikov, has not led to the birth of gene-edited babies—yet.

The authors have requested a retraction of a paper that found people with the CCR5 Δ32 variant are more likely to die sooner.

In the wake of reports of CRISPRed babies born in China, a bipartisan resolution “opposes the experiments that resulted in pregnancies using genome-edited human embryos.”

Researchers combine CRISPR technology with a graphene transistor to create an electronic sensor for particular DNA sequences.

A CRISPR-based electronic sensor flags target DNA sequences at high speed.

Emails reveal that a facility in Dubai and others have asked geneticist He Jiankui for help in gene-editing embryos.

Machine learning algorithms predict the repairs made to DNA after Cas9 cuts.

CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.

After the controversy of a Chinese scientist who was involved in editing the genomes of twin girls, the country puts forth tighter guidelines.

The group had argued that a patent given to the Broad Institute overlapped with this one.

Researchers edited macaque embryos to induce symptoms of sleep disorders and chose one animal to clone. A bioethicist questions the study’s appropriateness.