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Removing a specific miRNA from stem cells may induce the expression of endogenous retroviruses that enable the cells to form extra-embryonic lineages.

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image: Induced Pluripotent Stem Cells Show Signs of Donor Age

Induced Pluripotent Stem Cells Show Signs of Donor Age

By | December 12, 2016

iPSCs created through the reprogramming of human somatic cells retain genomic marks of the donor’s age.

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image: Naive T Cells Find Homes in Lymphoid Tissue

Naive T Cells Find Homes in Lymphoid Tissue

By | December 2, 2016

The human lymph nodes and spleen maintain unique, compartmentalized sets of naive T cells well into old age.

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image: Culprit for Antibody Blockade Identified

Culprit for Antibody Blockade Identified

By | October 21, 2016

Type I interferon organizes several immune mechanisms to suppress B cell responses to a chronic viral infection.

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image: Nixing NETs to Prevent Metastasis

Nixing NETs to Prevent Metastasis

By | October 19, 2016

Researchers discover that neutrophil extracellular traps help cancers spread, and design enzyme-loaded nanoparticles to destroy them.

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image: Who Is Immune to Zika?

Who Is Immune to Zika?

By | October 11, 2016

Researchers tap into ongoing dengue studies to improve antibody-based diagnostic tests for Zika and address unanswered questions about the emerging virus’s epidemiology.

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Matching the immunological characteristics of donor retinal cells to those of the recipient can reduce the chance of rejection.

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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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image: Zika Infects Adult Neural Progenitors Too

Zika Infects Adult Neural Progenitors Too

By | August 18, 2016

A mouse study shows that the virus has tropism for adult proliferative neural progenitor cells and immature neurons.

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