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Chemistry Nobel goes to Jacques Dubochet, Joachim Frank, and Richard Henderson. 

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image: Nonviral CRISPR Delivery a Success

Nonviral CRISPR Delivery a Success

By | October 2, 2017

Researchers use gold nanoparticles to deliver CRISPR-Cas9 and correct a point mutation in a mouse model of Duchenne muscular dystrophy. 

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image: Metabolomics Data Under Scrutiny

Metabolomics Data Under Scrutiny

By | September 15, 2017

Out of 25,000 features originally detected by metabolic profiling of E. coli, fewer than 1,000 represent unique metabolites, a study finds.

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image: Quantitating Glycans for Biomarker Discovery

Quantitating Glycans for Biomarker Discovery

By | August 28, 2017

Techniques for comparing the relative abundances of glycans and glycoproteins in clinical samples

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image: Vitamin C Depletion Accelerates Leukemia in Mice

Vitamin C Depletion Accelerates Leukemia in Mice

By | August 21, 2017

High levels of vitamin C absorbed by blood-forming stem cells are important for their normal development. 

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image: Custom-Made Molecules

Custom-Made Molecules

By | August 21, 2017

A new prototype machine can make the biological molecules of one’s choice from digital DNA sequences.

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image: Vitamin C Blocks Leukemia Progression in Mice

Vitamin C Blocks Leukemia Progression in Mice

By | August 17, 2017

High-dose vitamin C injections reverse the effects of a leukemia-promoting genetic deficiency.

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image: The Cancer Genes Needed for Immunotherapy Response

The Cancer Genes Needed for Immunotherapy Response

By | August 7, 2017

Using a large CRISPR-based screen, researchers find possible genetic culprits for patients not having success with immune checkpoint inhibitors.  

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image: The Ever-Expanding T-Cell World: A Primer

The Ever-Expanding T-Cell World: A Primer

By | August 7, 2017

Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.

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image: Chemogenetics Doesn’t Work Like Many Thought

Chemogenetics Doesn’t Work Like Many Thought

By | August 4, 2017

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

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