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image: The RNA Age: A Primer

The RNA Age: A Primer

By | May 11, 2017

Our guide to all known forms of RNA, from cis-NAT to vault RNA and everything in between.

7 Comments

image: Genome Digest

Genome Digest

By | May 11, 2017

What researchers are learning as they sequence, map, and decode species’ genomes

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image: Opinion: Get to Know Why People Openly Share Genomic Data

Opinion: Get to Know Why People Openly Share Genomic Data

By | May 9, 2017

It’s not only about health but also about exploring ancestry and contributing to science.

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By implanting patient- or rodent-derived mini-guts into mice, scientists can rapidly create more-accurate murine models of the disease

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image: CRISPR Corrects Duchenne-Causing Mutations

CRISPR Corrects Duchenne-Causing Mutations

By | April 12, 2017

Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.

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Octopus, cuttlefish, and squid extensively edit messenger RNAs in an evolutionarily conserved process. 

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image: Cross-Sample Sequencing Contamination Galore

Cross-Sample Sequencing Contamination Galore

By | April 5, 2017

Scientists conducting a large-scale, comparative transcriptomics project have inadvertently highlighted widespread contamination in sequencing data.

3 Comments

image: CRISPR Screen Detects Functional Gene Regulation

CRISPR Screen Detects Functional Gene Regulation

By | April 3, 2017

A CRISPR-Cas9–based method probes the regulatory roles of noncoding DNA sequences.

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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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image: Should Healthy People Have Their Exomes Sequenced?

Should Healthy People Have Their Exomes Sequenced?

By | March 24, 2017

With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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