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Studies of infected rhesus monkeys reveal the virus’s long-term hiding places in the body.

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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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image: Should Healthy People Have Their Exomes Sequenced?

Should Healthy People Have Their Exomes Sequenced?

By | March 24, 2017

With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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image: Pathway to Polio Virulence Revealed

Pathway to Polio Virulence Revealed

By | March 23, 2017

Using epidemiological and laboratory data, scientists have mapped out a sequence of mutations through which the attenuated oral polio vaccine reverts to a virulent virus.

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image: Inflammation Drives Gut Bacteria Evolution

Inflammation Drives Gut Bacteria Evolution

By | March 16, 2017

Viruses within Salmonella rapidly spread genes throughout the bacterial population during a gut infection, scientists show.

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image: Cortical Interneurons Show Layer-Specific Activities

Cortical Interneurons Show Layer-Specific Activities

By | March 2, 2017

Researchers examine the firing patterns of interneurons throughout all layers of the somatosensory cortices of alert mice.  

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image: How Bacteria Interfere with Insect Reproduction

How Bacteria Interfere with Insect Reproduction

By | February 28, 2017

Scientists identify the genes responsible for bacteria-controlled sterility in arthropods.

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image: Abundant Sequence Errors in Public Databases

Abundant Sequence Errors in Public Databases

By | February 16, 2017

A new algorithm reveals hoards of preparation-induced DNA mutations in publicly available human sequences.

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image: Broad Wins CRISPR Patent Interference Case

Broad Wins CRISPR Patent Interference Case

By | February 15, 2017

The USPTO’s Patent Trial and Appeal Board has ruled in favor of the Broad Institute of MIT and Harvard retaining intellectual property rights covered by its patents for CRISPR gene-editing technology.

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image: Toward Killing Cancer with Bacteria

Toward Killing Cancer with Bacteria

By | February 8, 2017

Researchers employ an engineered microbe to destroy tumor cells in mice.

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