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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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image: Should Healthy People Have Their Exomes Sequenced?

Should Healthy People Have Their Exomes Sequenced?

By | March 24, 2017

With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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image: Pathway to Polio Virulence Revealed

Pathway to Polio Virulence Revealed

By | March 23, 2017

Using epidemiological and laboratory data, scientists have mapped out a sequence of mutations through which the attenuated oral polio vaccine reverts to a virulent virus.

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image: Inflammation Drives Gut Bacteria Evolution

Inflammation Drives Gut Bacteria Evolution

By | March 16, 2017

Viruses within Salmonella rapidly spread genes throughout the bacterial population during a gut infection, scientists show.

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image: Abundant Sequence Errors in Public Databases

Abundant Sequence Errors in Public Databases

By | February 16, 2017

A new algorithm reveals hoards of preparation-induced DNA mutations in publicly available human sequences.

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image: Toward Killing Cancer with Bacteria

Toward Killing Cancer with Bacteria

By | February 8, 2017

Researchers employ an engineered microbe to destroy tumor cells in mice.

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image: Non-Chromosomal DNA Drives Tumor Evolution

Non-Chromosomal DNA Drives Tumor Evolution

By | February 8, 2017

Researchers discover that short pieces of DNA harboring oncogenes are relatively widespread in cancer.

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image: Restoring a Native Island Habitat

Restoring a Native Island Habitat

By | January 30, 2017

Removal of non-native vegetation from an island ecosystem revives pollinator activity and, in turn, native plant growth. 

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image: Lipids Take the Lead in Metastasis

Lipids Take the Lead in Metastasis

By | January 20, 2017

Researchers find diverse ways that the molecules can regulate cancer’s spread.

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A cell phone–based microscope can identify mutations in tumor tissue and image products of DNA sequencing reactions.

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