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image: Developing Brains in Dishes

Developing Brains in Dishes

By | April 26, 2017

Two studies report methods to mimic human fetal brain development using neurons derived from human induced pluripotent stem cells that form 3-D, brain-like structures. 

1 Comment

image: CRISPR Corrects Duchenne-Causing Mutations

CRISPR Corrects Duchenne-Causing Mutations

By | April 12, 2017

Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.

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By examining brainwave patterns in a posterior cortical area, scientists can predict when people are dreaming.

4 Comments

By converting glial cells into dopaminergic neurons, scientists were able to partially rescue motor behavior in mice.

3 Comments

Octopus, cuttlefish, and squid extensively edit messenger RNAs in an evolutionarily conserved process. 

1 Comment

image: Cross-Sample Sequencing Contamination Galore

Cross-Sample Sequencing Contamination Galore

By | April 5, 2017

Scientists conducting a large-scale, comparative transcriptomics project have inadvertently highlighted widespread contamination in sequencing data.

4 Comments

image: CRISPR Screen Detects Functional Gene Regulation

CRISPR Screen Detects Functional Gene Regulation

By | April 3, 2017

A CRISPR-Cas9–based method probes the regulatory roles of noncoding DNA sequences.

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image: Should Healthy People Have Their Exomes Sequenced?

Should Healthy People Have Their Exomes Sequenced?

By | March 24, 2017

With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

1 Comment

The University of Rhode Island neurotoxicologist and dean came to the U.S. for college in the 1980s. 

2 Comments

Mitochondrial DNA polymerase is necessary for the destruction of paternal mtDNA in fruit fly sperm, scientists show.

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