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image: Shotgun Sequencing Outdone by Amplicon

Shotgun Sequencing Outdone by Amplicon

By | August 8, 2017

The shotgun approach, typically thought to be the superior method, may substantially underestimate diversity in environments that have not already been classified, researchers find.

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image: A Potential Remedy for the Aging Brain

A Potential Remedy for the Aging Brain

By | August 8, 2017

In mice, injected fragments of a naturally occurring protein boost memory in young and old animals and improve cognition and mobility in a model of neurodegenerative disease. 

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image: The Sleeping Brain Can Learn

The Sleeping Brain Can Learn

By | August 8, 2017

Humans can remember new sensory information presented during REM sleep, but this ability is suppressed during deep, slow-wave slumber.

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image: A Database of Genetic Differences Among Lab Mice

A Database of Genetic Differences Among Lab Mice

By | August 7, 2017

Researchers have catalogued mutations in the coding regions of 36 of the most important mouse strains.

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image: The Cancer Genes Needed for Immunotherapy Response

The Cancer Genes Needed for Immunotherapy Response

By | August 7, 2017

Using a large CRISPR-based screen, researchers find possible genetic culprits for patients not having success with immune checkpoint inhibitors.  

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image: The Ever-Expanding T-Cell World: A Primer

The Ever-Expanding T-Cell World: A Primer

By | August 7, 2017

Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.

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image: Open Access On the Rise: Study

Open Access On the Rise: Study

By | August 7, 2017

The Scientist sat down with one of the authors of a recent analysis that quantifies the increasing incursion of open-access content into the world of scholarly publishing.

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image: Chemogenetics Doesn’t Work Like Many Thought

Chemogenetics Doesn’t Work Like Many Thought

By | August 4, 2017

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

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image: Skin Graft-based Gene Therapy Treats Diabetes in Mice

Skin Graft-based Gene Therapy Treats Diabetes in Mice

By | August 4, 2017

A small patch of engineered cells makes an enzyme that stimulates insulin release.

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image: Fascinated by Folding

Fascinated by Folding

By | August 4, 2017

Lila Gierasch uses biochemical tools to understand how linear chains of amino acids turn into complex three-dimensional structures.

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