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Stress alarm

By | June 22, 2001

Phosphorylation of the human checkpoint protein hRad17 signals DNA damage.

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the cause of fever after platelet transfusion?

By | June 22, 2001

The level of CD40 ligand in stored platelet concentrates is similar to human blood levels during inflammation and may explain febrile responses to transfusions.

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New class of rhizobia-forming bacteria identified

By | June 21, 2001

A second class of the Proteobacteria can form rhizobia, suggesting this ability is more widespread than previously thought.

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No horizontal transfer

By | June 21, 2001

Phylogenetic analysis refutes previous suggestions that there was extensive horizontal gene transfer from bacteria to vertebrates.

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The number of babies born in the US with neural tube defects has fallen dramatically following folic acid fortification of foodstuffs.

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genomics

By | June 20, 2001

microarrays can be used to study related bacteria for which complete genome sequences are not available.

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plays a pivotal role in pulmonary fibrosis

By | June 20, 2001

Pulmonary fibrosis is considered a deleterious consequence of persistent lung inflammation, but the mechanism by which inflammation leads to fibrosis remains incompletely understood. In June 15 Journal of Clinical Investigation, Martin Kolb and colleagues from McMaster University, Ontario, Canada, show how acute tissue injury in the lung — initiated by a highly proinflammatory cytokine — IL-1β, converts to progressive fibrotic changes.Kolb et al. used adenoviral gene transfer to

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Sickle cell adhesion mechanism

By | June 20, 2001

induced signal transduction.

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Evolutionary ESTs

By | June 19, 2001

Comparative analysis of expressed sequence tags (ESTs) identifies rapidly evolving proteins in the reproductive glands of male flies.

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Step-by-step account of HIV-1 infection

By | June 19, 2001

In response to HIV-1 infection immune cells decrease mRNA synthesis, suppress DNA repair gene transcripts and increase expression of apoptosis inducing genes.

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