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Hear today, gone the day after tomorrow

By | August 22, 2002

Continuous stereocilia remodelling explains the duration of post-concert tinnitus.

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Microsporidial mitochondrial remnants

By | August 22, 2002

Small mitochondria in a human parasite suggest the organelle is needed even when its aerobic respiration function is lost.

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Paternal mitochondrial DNA?

By | August 22, 2002

New evidence suggests that mitochondrial DNA can be paternally inherited.

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Gene therapy monkey business

By | August 21, 2002

New adeno-associated viruses isolated from monkeys may provide safe vectors for gene therapy.

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New Smithsonian science chief

By | August 21, 2002

David L. Evans leaving NOAA to administer diverse Institute research facilities.

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T cells keep the memory alive

By | August 21, 2002

The discovery of T cell functional plasticity could help treat autoimmune disorders and cancer.

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Transgene switch

By | August 21, 2002

The ability to regulate transgene expression levels is essential for many functional genomic and therapeutic applications. In an Advanced Online Publication in Nature Biotechnology, Wilfried Weber and colleagues describe the development of E.REX, a novel gene regulation system that exploits components of the Escherichia coli erythromycin-resistance regulon (Nat Biotechnol 2002, DOI:10.1038/nbt731).They designed both EOFF and EON systems that are respectively repressed or induced using macrolide

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Distinct Ras requirements

By | August 20, 2002

Ras oncogenesis differs between human and mouse cells.

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Failure for EGFR inhibitor

By | August 20, 2002

AstraZeneca releases disappointing results from trials of Iressa, a promising cancer drug.

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New, tacky oncogenes

By | August 20, 2002

Nr-CAM, a neuronal cell adhesion molecule, plays a role in melanoma and colon cancer.

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