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Wave of schizophrenic brain loss uncovered

By | September 26, 2001

Schizophrenic teenagers undergo a wave of grey matter loss that envelopes increasing amounts of the cortex throughout adolescence.

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A fish a day keeps the doctor away

By | September 25, 2001

Changes in the diet of the Inuit people of Nunavik, Canada, help explain the beneficial effect of n-3 fatty acids on the key risk factors of cardiovascular disease.

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Red squirrels in Britain

By | September 25, 2001

Red squirrels (Sciurus vulgaris) thrive in the north of England and Scotland and occupy a patchwork of highly fragmented woodland habitats. In the September 21 Science, Marie Hale and colleagues from the University of Newcastle, UK, report a genetic investigation of the impact of habitat fragmentation on British red squirrel populations (Science 2001, 293:2246-2248).They assembled over 100 squirrel samples collected between 1918 and 2000 and analysed four polymorphic microsatellite loci for each

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US agreement clarifies the use of stem cells in research

By | September 25, 2001

Agreement enables basic stem cell research to continue but bans diagnostic or therapeutic applications.

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Cod origins

By | September 24, 2001

Identifying the population origins of individual fish is important in assisting the policing of fishing waters and the tracking down of poachers. In the September 20 Nature, Einar Nielsen and colleagues from the Danish Institute for Fisheries Research describe a simple approach using microsatellite markers to assign individual Atlantic cod fish (Gadas morhua) to their original population (Nature 2001, 413:272).They studied three cod populations; from the North Sea, the Baltic Sea, and the northe

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Long term memory signals

By | September 24, 2001

The neural activity signaled by calcium/calmodulin-dependent protein kinase IV plays an important role in maintaining long-term memories.

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New pathway to understanding circadian rhythms

By | September 24, 2001

The mechanism that keeps track of time in our body is based on a perpetual secretion of clock proteins in a 24-hour feedback loop. But the signaling molecules that control this clock are largely unknown. In September 21 Science Julie Williams and colleagues from Howard Hughes Medical Institute, show that that the protein produced by Drosophila version of the neurofibromatosis-1 (Nf1) gene controls the circadian machinery via the Ras/MAPK signaling pathway.Williams et al. studied Drosophila with

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Novel protein controlling bacterial tryptophan production

By | September 21, 2001

Many bacterial species recognize the amino acid tryptophan and its transfer RNA as a regulatory signal responsible for tryptophan biosynthesis. In September 14 Science, Angela Valbuzzi and Charles Yanofsky from the Department of Biological Sciences, Stanford University determined that, in addition to sensing the amount of tryptophan present, Bacillus subtilis also has a mechanism for detecting the concentration of tryptophan-specific tRNA.Valbuzzi & Yanofsky discovered that if the amount of

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Of hippopotami and whales

By | September 21, 2001

New Eocene fossils discovered in Pakistan suggest that whales evolved from hippopotamuses.

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Staphylococcus

By | September 21, 2001

Although many gene-inactivation technologies have been applied to bacterial genetics, the potential for using antisense technology has not been extensively explored. In the September 21 Science, Yindo Ji and colleagues from GlaxoSmithKline Pharmaceuticals in Collegeville, Pennsylvania, describe a comprehensive genomic analysis of the human pathogen Staphylococcus aureus using a regulated antisense strategy (Science 2001, 293:2266-2269).They used an adapted tetracycline-dependent (tet) regulatory

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