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Animal applications easier

By | August 27, 2002

New NIH policy streamlines grant procedure for animal research.

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BRCA1 enhances repair

By | August 27, 2002

The BRCA1 protein specifically enhances the global genomic repair pathway and induces DNA repair gene expression.

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Chicken flu circumvents cytokines

By | August 27, 2002

The avian H5N1 influenza virus outbreak in Hong Kong in 1997 proved to be highly virulent when first transmitted to humans, but the reasons for this virulence have remained unclear. In August 26 Nature Medicine, Sang Heui Seo and colleagues at St Jude Children's Research Hospital, Memphis, USA, show that lethal H5N1 influenza viruses, unlike other human, avian and swine influenza viruses, are resistant to the antiviral effects of interferons and tumor necrosis factor α (Nat Med 2002, DOI:10

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Monsanto's misery

By | August 27, 2002

The GM giant scales down its plans for growth in Europe in the face of public opposition to its products.

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Parkinson's Disease initiative

By | August 27, 2002

NIEHS awards multi-center grant to study gene-environment connections.

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Small RNAs in yeast

By | August 27, 2002

Small RNAs isolated from fission yeast map to centromeric repeats and may be involved in epigenetic regulation.

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Telomerase shuttling

By | August 27, 2002

Telomerase undergoes regulated intranuclear shuttling during the cell cycle.

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Bone to brain change fails

By | August 23, 2002

Early reports that adult mouse bone marrow cells (BMCs) were capable of transdifferentiating into cells with neural characteristics in the central nervous system raised hopes of developing effective treatments for neurodegenerative disorders. But, in August 23 Science, Raymond Castro and colleagues at Baylor College of Medicine, Houston, US, show that bone marrow cells from mice do not transdiferentiate into neural cells in vivo (Science 2002, 297:1299).Castro et al. used C57Bl/6 (B6) mice, whic

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Envelope clue to general HIV vaccine

By | August 23, 2002

HIV envelope glycoprotein complexes elicit broadly cross-reactive neutralizing antibodies in rhesus macaques.

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Fungal double whammy

By | August 23, 2002

A fungal saponin-detoxifying enzyme mediates a two-step suppression of plant defenses.

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