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Can sequences turn a profit?

By | May 16, 2002

The public release of the draft mouse genome sequence reopens the debate on the commercial viability of genome sequencing.

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Small molecule clears amyloid

By | May 16, 2002

A novel compound that increases the clearance of amyloid deposits could be useful in the treatment of human amyloidosis.

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From genes to disease

By | May 15, 2002

Only a small fraction of the thousands of described genetically inherited diseases have been linked to a specific gene. In an Advanced Online Publication in Nature Genetics Carolina Perez-Iratxeta and colleagues at the EMBL in Heidelberg describe using a bioinformatics approach to link genes to diseases (Nat Genet 2002, DOI:10.1038/ng895).Their data-mining system is based on 'fuzzy set theory', which can make inferences from the complex scientific literature. They integrated information from mul

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Changing somatic cell function

By | May 14, 2002

Functional reprogramming of somatic cells can be achieved using a nuclear and cytoplasmic extract derived from another somatic cell type.

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Chromatin control during the cell cycle

By | May 14, 2002

A large macromolecular complex regulates chromatin conformation and gene transcription during the cell cycle.

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Finding the needle in the haystack

By | May 14, 2002

A new method for searching for antibiotics isolates compounds with inhibitory activity against more than one essential target.

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2002 Royal Society Fellows

By | May 13, 2002

The UK's Royal Society has announced the election of 42 new Fellows and six Foreign Members.

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Choosing the X

By | May 13, 2002

Inactivation of one of the two X chromosomes in females is regulated by sequences on the X-chromosome within the X inactivation center (Xic). In the May 10 Science, Percec et al. report the identification of trans-acting autosomal elements involved in choosing the particular X chromosome for inactivation (Science 2002, 296:1136-1139).They performed a phenotype-driven genetic screen for mutations that affect X-chromosome silencing choices in mice: they screened mice from parents exposed to chemic

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IGF-I may heal diabetes

By | May 13, 2002

cells regenerates pancreatic islets and leads to recovery from type 1 diabetes.

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Choosy stem cell migration

By | May 10, 2002

but not to chemokines signaling through other chemokine receptors.

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