Bacteria in the intestine influence motor dysfunction and neuroinflammation in a mouse model of Parkinson’s disease.
April 3, 2002|
Group A Streptococcus (GAS) infection by serotype M18 strains causes acute rheumatic fever (ARF) and can lead to pediatric heart disease. In the April 2 Proceedings of the National Academy of Sciences, James Smoot and colleagues at the National Institute of Allergy and Infectious Diseases report the genome sequence of a GAS strain (MGAS8232) isolated from a patient with ARF (Proc Natl Acad Sci USA 2002, 99:4668-4673).Smoot et al. compared the 1.9 Mb genome with a closely related strain (the M1 s