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Cellular Research
Cellular Research

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Covering the life sciences inside and out

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A new mechanism for hypertension

By | October 3, 2001

Mitochondrial coupling factor 6 is a potent circulating endogenous vasoconstrictor, producing hypertension by suppressing prostacyclin synthesis.

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Making healthy new blood vessels

By | October 3, 2001

can induce the formation of new blood vessels that do not show signs of leakage or inflammation.

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pol II

By | October 3, 2001

plays a critical role during transcription by RNA polymerase II.

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Protein that affects susceptibility to anthrax

By | October 3, 2001

Kif1C, a kinesin-like motor protein, protects mice macrophages from the lethal effects of anthrax.

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Dynamic auxin efflux carriers

By | October 2, 2001

The transport of the hormone auxin through plant cells may be a more dynamic process than previously thought.

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Telomerase mutations

By | October 2, 2001

Patients with dyskeratosis congenita suffer from defects in skin, nails, hair and gut, and usually die from bone-marrow failure. An X-linked form of the disease is due to mutations in the DKC1 gene that encodes dyskerin, a protein associated with small nucleolar RNAs and telomerase RNA (hTR). In the September 27 Nature, Tom Vulliamy and researchers at Imperial College and the Hammersmith Hospital, London, UK, identify mutations that cause autosomal dominant dyskeratosis congenita (Nature 2001, 4

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Germ warfare

By | October 1, 2001

The attack on the World Trade Center has increased speculation that populations could be at risk from terrorist attacks with biological and chemical weapons.

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Muscle profiles

By | October 1, 2001

Different skeletal myofibre types are known to express distinct muscle myosin isoforms. In the Early Edition of the Proceedings of the National Academy of Sciences, Porter et al., from Case Western Reserve University, Cleveland, USA, describe a genomics approach to exploring the molecular signatures underlying skeletal muscle biology (Proc Natl Acad Sci USA 2001, 10.1073/pnas.211257298).They used high-density oligonucleotide arrays (from Affymetrix) to measure gene expression profiles in the ext

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Organ development signals from the vasculature

By | October 1, 2001

Blood vessels are an essential, but largely passive infrastructure for organ development, supplying metabolic provisions to the dividing cells. But, in September 28 on line Science, Eckhard Lammert and colleagues from Howard Hughes Medical Institute, Harvard University, show that during pancreatic organogenesis blood vessels not only provide metabolic provisions but also offer inductive signals for organ development.Lammert et al. performed cell culture experiments with embryonic mouse tissue an

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Cells whisper

By | September 28, 2001

Cells respond within a millisecond to changes in membrane voltage, emitting sounds whilst they fulfil their function.

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