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Virus-induced RNA silencing

By | May 20, 2002

RNA silencing processes result in the sequence-specific degradation of RNA and effective post-transcriptional gene silencing. In the May 17 Science, Hongwei Li and colleagues from the University of California, Riverside report that Flock House Virus (FHV) is both an initiator and a target of RNA silencing (Science 2002, 296:1319-1321).Li et al. observed that B2 gene of FHV resembles a plant virus gene encoding a silencing suppressor. Expression of the FHV B2 protein in plants prevented RNA silen

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Bacterial ancestors

By | May 17, 2002

Analysis of ribosomal RNA sequences in bacteria suggests that the earliest organisms were not hyperthermophiles.

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A WiNTers tale

By | May 16, 2002

NF-AT transcription factor acts as a downstream component of the WNT/calcium signaling pathway.

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Can sequences turn a profit?

By | May 16, 2002

The public release of the draft mouse genome sequence reopens the debate on the commercial viability of genome sequencing.

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Small molecule clears amyloid

By | May 16, 2002

A novel compound that increases the clearance of amyloid deposits could be useful in the treatment of human amyloidosis.

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From genes to disease

By | May 15, 2002

Only a small fraction of the thousands of described genetically inherited diseases have been linked to a specific gene. In an Advanced Online Publication in Nature Genetics Carolina Perez-Iratxeta and colleagues at the EMBL in Heidelberg describe using a bioinformatics approach to link genes to diseases (Nat Genet 2002, DOI:10.1038/ng895).Their data-mining system is based on 'fuzzy set theory', which can make inferences from the complex scientific literature. They integrated information from mul

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Changing somatic cell function

By | May 14, 2002

Functional reprogramming of somatic cells can be achieved using a nuclear and cytoplasmic extract derived from another somatic cell type.

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Chromatin control during the cell cycle

By | May 14, 2002

A large macromolecular complex regulates chromatin conformation and gene transcription during the cell cycle.

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Finding the needle in the haystack

By | May 14, 2002

A new method for searching for antibiotics isolates compounds with inhibitory activity against more than one essential target.

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2002 Royal Society Fellows

By | May 13, 2002

The UK's Royal Society has announced the election of 42 new Fellows and six Foreign Members.

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