Bacteria in the intestine influence motor dysfunction and neuroinflammation in a mouse model of Parkinson’s disease.
February 28, 2002|
Patients infected with HIV have highly variable CD8+ CTL responses despite the high number of circulating CD8+ T cells, an observation that remains poorly understood. In March Journal of Immunology Mohammed Garba and colleagues from University of North Carolina, Chapel Hill, USA, show that the failure of CD8+ T cell responses can be the result of an active HIV regulatory process mediated by secretion of TGF-β1, rather than the absence of CD8+ cells.Garba et al. used flow cytometric methods