The USPTO’s Patent Trial and Appeal Board has ruled in favor of the Broad Institute of MIT and Harvard retaining intellectual property rights covered by its patents for CRISPR gene-editing technology.
April 10, 2002|
The mechanism by which a linear sequence of amino acids controls the folding of a protein into its unique three-dimensional structure remains incompletely understood. In April 8 online Nature Structural Biology, Christian Wigley and colleagues from University of Texas Southwestern Medical Center, Dallas, show that a protein sequence can encode the native structure by disfavouring the formation of a misfolded structure.Wigley et al. observed that a proline residue in the center of the third trans