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Why too much sex isn't good in the long run

By | February 14, 2001

when you're a ram, that is.

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Pneumococcal vaccine protects children from otitis

By | February 13, 2001

The frequent ear infections suffered by some infants during the first two years of life can be difficult to treat. Most are caused by Streptococcus pneumoniae, also responsible for chest infections in adults and for which there is already a vaccine. A team from the National Public Health Institute, Helsinki, Finland tested the efficacy of the new conjugate pneumococcal vaccine in children and found that it can also be effective in the prevention of ear infections (N Engl J Med 2001, 344:403-409)

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Pressure for cheaper AIDS drugs increases

By | February 13, 2001

res at a daily treatment cost of less than one dollar.

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The cause of proteinuria in polycystic kidney disease

By | February 13, 2001

Portions of cyst-lining epithelia in the proximal tubules have lost the ability to endocytose and thus cannot reabsorb low-molecular-weight proteins.

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The Celera paper: sequencing by random shotgun cloning

By | February 13, 2001

In the February 16 Science, Venter et al. announce the sequencing of the euchromatic portion of the human genome by a whole-genome shotgun sequencing approach (Science 2001, 291:1304-1350). The sequencing achievement was accomplished by Celera Genomics in nine months in a factory-scale project involving 300 automatic squencing machines (ABI PRISM 3700) producing 175,000 sequence-reads per day. The company generated 14.8 gigabases (Gb) of DNA sequence and combined data with the public GenBank) da

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The Human Genome Consortium paper: sequencing by collaborative mapping

By | February 13, 2001

In the February 15 Nature, the International Human Genome Sequencing Consortium announces the completion of the first draft of the sequence of the human genome. The publication is the achievement of the decade-long Human Genome Project based on open international collaboration (involving 20 groups) and rapid, unrestricted data release (via GenBank). The draft sequence covers 94% of the genome, which is estimated to be about 3.2 Gigabases (Gb), 25 times the size of any previously sequenced genome

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Endotoxin role in airway disease

By | February 12, 2001

Inhalation of corn dust extract results in the development of chronic airway disease in mice sensitive to endotoxin but not in mice that are genetically hyporesponsive to endotoxi.

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let the debate begin

By | February 12, 2001

of papers laying bare the human genome brings the first chapter of genomic research towards its completion. Once the happy handshakes are over the real business will start. It'll be up to policy makers to grapple with the implications and scientists to see whether all the effort was worthwhile.

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Mechanism of heat stroke

By | February 12, 2001

Hyperthermia stimulates xanthine oxidase production of reactive oxygen species that limit heat tolerance by promoting circulatory and intestinal barrier dysfunction..

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MMR is not linked with autism

By | February 12, 2001

A new study concludes that MMR is not linked to autism because the incidence of autism continued to increase among boys from 1988 to 1993 while the MMR vaccine coverage in the UK was virtually constant.

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