News & Opinion

Covering the life sciences inside and out

Most Recent

Vitamin heart protection role revealed

By | October 31, 2001

Vitamin C could protect against heart disease by reducing apoptosis in vascular epithelial cells.

0 Comments

Dendritic defence

By | October 30, 2001

Dendritic cells (DCs) are stalwarts of the immune response, activating both the innate and acquired immune systems. In the October 26 Science Qian Huang and colleagues at the Whitehead Institute for Biomedical Research describe the use of oligonucleotide microarrays to examine how DCs respond to different pathogens (Science 2001, 294:870-875).They exposed human monocyte-derived DCs to Gram-negative bacteria (Escherichia coli), fungi (Candida albicans) or an RNA virus (influenza virus), and then

0 Comments

Fugu genome rough draft completed

By | October 30, 2001

The announcement of the completion of the sequencing of the puffer fish genome will help analysis of the human genome.

0 Comments

Insurance companies announce genetic testing halt

By | October 30, 2001

A five-year moratorium on the use of genetic test results in the calculation of insurance premiums has provided some much needed breathing space.

0 Comments

The multifunctional hairless gene

By | October 30, 2001

gene is capable of regulating its own expression, and that of other genes.

0 Comments

Altered cryopyrin brings fever and chills

By | October 29, 2001

Wells syndromes.

0 Comments

Chaperones for virulent bacterial proteins

By | October 29, 2001

The type III bacterial chaperones protect the harmful proteins produced by pathogenic bacteria until they are delivered across membranes into the host cell. In October 29 on line Nature Structural Biology, Yu Luo and colleagues from University of British Columbia, Canada report the structures of three type III chaperones, providing important details about the function of the proteins and the mechanisms employed to modulate the virulence of invasive bacteria.Luo et al. reported the crystal struct

0 Comments

Switching on genes with GeneSwitch

By | October 29, 2001

Fruitfly biologists have developed some elaborate genetic tricks to express transgenes in a spatially restricted manner. The bipartite GAL4/UAS system exploits the yeast GAL4 transcriptional activator and the upstream activating sequence (UAS) to which it binds to drive transgene expression. In the October 23 Proceedings of the National Academy of Sciences, Thomas Osterwalder and colleagues at Yale University describe an enhanced conditional, tissue-specific expression system that can take advan

0 Comments

Fast protein translation to release memories

By | October 26, 2001

The maps of electrical brain activity taken during the making of memories are well established, but how those memories are stored and subsequently released remains unclear. In 23 October Proceedings of the National Academy of Science, Christy Job and James Eberwine from University of Pennsylvania School of Medicine show how neuronal dendrites use a fast translation mechanism for protein manufacture in a part of the brain devoted to making and storing memories.Job & Eberwine used multiphoton

0 Comments

Lining-up Listeria genomes

By | October 26, 2001

Listeriosis is caused by the ingestion of pathogenic Listeria monocytogenes in contaminated food. In the October 26 Science, Glaser et al. report a comparative analysis of Listeria genomes aimed at identifying virulence genes (Science 2001, 294:849-852).They sequenced the genomes of two Listeria strains; pathogenic L. monocytogenes EGD-e and a non-virulent species L. innocua.L. monocytogenes contains a single circular chromosome of 2.9 Mb, while L. innocua has a 3 Mb chromosome and an 80 kb plas

0 Comments

Popular Now

  1. Neurons Compete to Form Memories
  2. Mapping the Human Connectome
    Daily News Mapping the Human Connectome

    A new map of human cortex combines data from multiple imaging modalities and comprises 180 distinct regions.

  3. The Genetic Components of Rare Diseases
  4. Classic Example of Symbiosis Revised
RayBiotech