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Nitric oxide holds the key to firefly glow

By | June 29, 2001

Nitric oxide was once regarded simply as a noxious pollutant. But its ever expanding functional repertoire may now include generation of firefly luminescence.

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TNF signalling in rheumatoid arthritis

By | June 29, 2001

Blocking tumour necrosis factor ligands inhibits both humoral and cellular immune mechanisms in a model of rheumatoid arthritis.

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Crenarchaeon genome

By | June 28, 2001

Sulfolobus solfataricus is a model organism for the study of the crenarchaeal branch of the Archaea. It is remarkable for its optimal growth conditions: 80oC and pH 2-4, metabolizing sulfur. In the July 3 Proceedings of the National Academy of Sciences, She et al. report completion of the genome sequence of S. solfataricus by a Canadian-European collaborative project (Proc Natl Acad Sci USA 2001, 98:7835-7840). The genome is almost 3 megabases long on a single chromosome and encodes 2977 protein

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ICOS role in suppressing organ rejection

By | June 28, 2001

An ICOS blockade suppresses intragraft T cell activation and cytokine expression and prolongs transplant survival.

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Signals in inflammation resolution

By | June 28, 2001

generated early in inflammation acts as an inducer of subsequent anti-inflammatory pathways partly by amplification of lipoxin expression.

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A thousand northerns

By | June 27, 2001

High-throughput northern hybridizations have generated a 'Rosetta Stone' of standardized reference data for yeast.

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GM patients inject hope into prostate cancer research

By | June 27, 2001

Modified common cold viruses are to be injected directly into prostate tissue, making the recipients officially genetically modified organisms.

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-methyl-D-aspartate receptors

By | June 26, 2001

N-methyl-D-aspartate receptors are involved in mediating the behavioural pain response to colonic distention in the normal rat colon.

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Cancer drug resistance

By | June 26, 2001

Leukemia patients who become resistant to anti-cancer drugs acquire mutations or amplifications of the initiating oncogene.

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Royal Society calls for moratorium on human reproductive cloning

By | June 26, 2001

has called for an international moratorium on human reproductive cloning.

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