News & Opinion

Covering the life sciences inside and out

Most Recent

ethical populist

By | September 7, 2001

discusses how he sees the future of electronic biomedical publishing.

0 Comments

Ink4a

By | September 7, 2001

The CDKN2A (INK4a/ARF) locus encodes two distinct cell cycle inhibitors, p16Ink4a and p19ARF, both of which have been implicated in tumorigenesis. In the September 6 Nature, two independent groups report the generation of knockout mice specifically lacking p16Ink4a. Surprisingly, mouse embryonic fibroblasts (MEFs) lacking p16Ink4a were normal in terms of growth characteristics, senescence phenotypes and resistance to oncogenic Ras-induced transformation.These observations are in contrast to resu

0 Comments

PLoS plans to publish its own journals

By | September 7, 2001

Thousands of scientists from around the world have signed up in support of the Public Library of Science call for free online access to all scientific journals. But will this support translate into action?

0 Comments

Hepatitis virus G inhibits HIV replication

By | September 6, 2001

Infection with hepatitis G virus improves survival in patients infected with HIV probably by directly influencing HIV replication.

0 Comments

Mitochondrial inheritance

By | September 6, 2001

In September 6 Nature, Sofia Berlin and Hans Ellegren from Uppsala University, Sweden, examine the controversial clonal inheritance theory for vertebrate mitochondrial DNA (mtDNA) by following co-inheritance of a female-specific nuclear DNA marker (Nature 2001, 413:37-38).They examined the avian W chromosome, most of which is non-recombining and therefore clonally transmitted by females. A polymorphic (CA)n repeat, NVHfp49, on the W chromosome of 53 female peregrine falcons (Falco peregrinus) an

0 Comments

stem cells to become blood

By | September 6, 2001

The potential of embryonic stem cells to develop into a wide variety of tissues and organs has been established, but it remains unclear how this can be achieved in practice. In 4 September Proceedings of the National Academy of Sciences, Dan Kaufman and colleagues at the University of Wisconsin-Madison show for the first time how undifferentiated human embryonic stem cells (ES) can be cultured to become blood cells.Kaufman et al. cultured ES in flasks containing murine bone marrow cell line S17

0 Comments

will require constant innovation

By | September 6, 2001

resistant to vancomycin and now linezolid illustrates the urgent need for novel antibiotic design strategies.

0 Comments

Following the cancer trail

By | September 5, 2001

Aggressive melanoma cells leave a molecular trail in the extracellular matrix enabling less aggressive cells to become more aggressive.

0 Comments

Protecting colonic mucosa

By | September 5, 2001

Short-chain fatty acids protect colonic mucosa against oxidant-induced stress through inducing expression of hsp25.

0 Comments

Career counselling for embryonic cells

By | September 4, 2001

In an embryo, the stem cells develop into specific organs under the influence of complex extracellular signals. Sonic hedgehog (Shh) plays an important role in this process but its signalling pathway is not entirely understood. In August 31 Science Gurtej Dhoot and colleagues from the University of Pennsylvania Medical Center identify a member of a family of conserved sulfatases, QSulf1, which is responsive to Shh signaling and has role in embryonic cell fate determination.Dhoot et al. identifie

0 Comments

Popular Now

  1. Monsanto Buys Rights to CRISPR
    The Nutshell Monsanto Buys Rights to CRISPR

    The US agribusiness secures a global, nonexclusive licensing agreement from the Broad Institute to use the gene-editing technology for agricultural applications.

  2. Does Productivity Diminish Research Quality?
  3. How Plants Evolved Different Ways to Make Caffeine
  4. ESP on Trial
    Foundations ESP on Trial

    In the 1930s, parapsychologist Joseph Banks Rhine aimed to use scientific methods to confirm the existence of extrasensory perception, but faced criticisms of dubious analyses and irreproducible results.

RayBiotech