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Zebrafish genome to be sequenced

By | November 23, 2000

The genome of the zebrafish is to be sequenced at the Wellcome Trust's Sanger Centre near Cambridge, UK.

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Zebrafish on drugs

By | November 23, 2000

In the November 21 Proceedings of the National Academy of Sciences, Peterson et al. describe a screen for chemicals that can be used to interfere with, and time, developmental events in zebrafish (Proc Natl Acad Sci USA 2000, 97:12965-12969). Zebrafish eggs were arrayed three to a well in 96-well plates, along with one of 1,100 synthetic small molecules. The developing embryos were screened once a day for three days for defects in the central nervous system, the cardiovascular system, pigmentat

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110m into post-genomic research

By | November 22, 2000

500,000 people will help research councils to solve post-genomic puzzles.

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Children's parents sue hospital over genetics patent

By | November 22, 2000

Families of children suffering a degenerative brain disease are suing the hospital and researchers who used their children's blood and tissue to identify and patent the gene responsible for the disorder.

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Genetic determinant for bronchiolitis virus

By | November 21, 2000

A particular allele of the IL-8 gene may be a determining factor for the severity of bronchiolitis among children. Most children are infected by the respiratory syncytial virus (RSV) that causes bronchiolitis by the age of two. For most bronchiolitis remains a mild illness but for some it can cause severe breathing problems and may require admission to hospital. The walls of airways infected with RSV have high levels of interleukin 8 (IL-8), a neutrophil chemoattractant which causes inflammation

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Italy: a GMO-free country?

By | November 21, 2000

The Italian Minister for Agricultural and Forestry Policy has made it clear he intends to ban GMOs of agricultural interest - but will he manage to sway the Italian public?

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HOUSTON "Mosquitoes are flying syringes," declared Frank Cortez-Flores of Loma Linda University (California), and two mosquito-borne diseases have broken past old geographic boundaries to invade the US. The first, West Nile encephalitis, is a newcomer to the western hemisphere and thus has garnered the most headlines. The other, dengue fever, is considered the world's most important vector-borne viral disease affecting people, in terms of both morbidity and mortality. The West Nile virus, native

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Interfering with worms

By | November 20, 2000

Two systematic RNAi screens in worms provide the first large-scale reverse genetic analyses of a multicellular organism.

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Killing me softly with his sperm

By | November 20, 2000

Inducing death in the mother of your future children may not be the wisest way to maximize your contributions to the gene pool. And yet male flies do just that: their sperm (or, more correctly, their seminal fluid) increases the death rate of recipient females. In the November 21 Proceedings of the National Academy of Sciences, Civetta and Clark suggest that the polygamous nature of fly society provides an explanation for this puzzling behavior. They find that male flies that induce a greater mo

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Nice and open

By | November 20, 2000

The UK's National Institute for Clinical Excellence has opted to remove confidentiality from its appraisal process as a means of pre-empting information leaks.

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