The USPTO’s Patent Trial and Appeal Board has ruled in favor of the Broad Institute of MIT and Harvard retaining intellectual property rights covered by its patents for CRISPR gene-editing technology.
October 15, 2001|
During T-lymphocyte activation, signals from a number of cell-surface receptors must be integrated to ensure the appropriate genetic response. Non-dividing, primary T lymphocytes are notoriously difficult to transfect, presenting an experimental limitation to dissecting signaling mechanisms. In the October issue of Nature Medicine, Michael Bell and colleaguess from the Mayo Clinic in Rochester, Minnesota, describe an efficient method for introducing DNA into non-dividing lymphocytes, so as to an