The largely overlooked resident fungal community plays a critical role in human health and disease.
May 8, 2001|
Large-scale methods for gene profiling or protein quantification are the focus of genomic and proteomic studies. But new approaches are needed to integrate these data sets and create biological models that can predict cellular behaviour. In the May 4 Science, Ideker and colleagues, at the Institute for Systems Biology in Seattle, describe an integrated approach to create a model of cellular metabolic pathways (Science 2001, 292:929-934). Their approach is based on four steps: defining all the ge