Biomedical engineer Kyle Quinn fends off a frenzied Internet mob after being wrongly identified as a Charlottesville protester.
December 14, 2001|
The vast majority of genes in the yeast genome are non-essential suggesting significant functional redundancy. In the December 14 Science, Amy Tong and colleagues describe an approach for high-throughput synthetic-lethal analysis in yeast (Science 2001, 294:2364-2368).They developed an ordered array of about 4,700 viable gene-deletion mutants and generated haploid double-mutants; they called this strategy synthetic genetic array (SGA) analysis. Tong et al. tested a query strain with a deletion i