Advertisement
Bethyl Laboratories
Bethyl Laboratories

News & Opinion

Covering the life sciences inside and out

Most Recent

Fear of legal action is hobbling research into a key AIDS threat, which may quadruple the numbers infected with HIV in China.

0 Comments

A gene identified in mice could encourage excess energy to be released as heat rather than converted to fat.

0 Comments

Simplifying genetic disorders

By | October 3, 2000

Recent work implicating a single gene in a population with a complex disease, type 2 diabetes mellitus, could represent a shift in the study of genetic diseases.

0 Comments

A protein kinase switch

By | October 2, 2000

Kinase inhibitors are plagued by a lack of specificity. Now in the 21 September Nature Bishop et al. tackle the problem by building on their earlier work, in which they modified the ATP-binding sites of Src-family tyrosine kinases to accept either nucleotide analogs or modified kinase inhibitors. In the new work the researchers mutate kinases from four distinct kinase families by replacing a bulky residue with a small residue. This change provides enough room for the binding of inhibitor analogs

0 Comments

Hedgehogs make both fish and fly eyes

By | October 2, 2000

The fly eye is patterned by a morphogenetic wave driven by the Hedgehog signaling protein. In the 22 September Science Neumann and Nuesslein-Volhard report that neuronal differentiation in zebrafish eyes is dependent on a similar wave of hedgehog proteins (Science 2000, 289:2137-2139). Previous work on Pax6 already indicated that the mechanism of eye induction is conserved across the animal kingdom. But variations in eye structure suggested that events downstream of eye induction must have evolv

0 Comments

Blood filtration improves safety of blood transfusions

By | September 28, 2000

White blood cells can cause costly complications following transfusions; the US and Germany are joining the list of countries requiring filtration of donor blood to remove them.

0 Comments

Two ACEs in the pack

September 28, 2000

A genomics-based approach has uncovered the first human homologue of ACE (angiotensin-converting enzyme).

0 Comments

Chromodomains bind RNA

By | September 27, 2000

Male flies compensate for having a single X chromosome by doubling the single X chromosome's level of expression. This increase is mediated by MOF, a histone H4 acetyltransferase. MOF, along with other proteins and an RNA called roX2, binds to the male X chromosome. In the 21 September Nature Akhtar et al. find that MOF and another dosage compensation protein called MSL-3 use their chromodomains to bind to roX2 and thus to the male X (Nature 2000, 407:405-409). Other chromodomain proteins, which

0 Comments

Dietary fat restriction in infancy could prevent the development of coronary heart disease in adulthood.

0 Comments

A gene has been discovered that could make people with defective copies three times more likely to develop type 2 diabetes.

0 Comments

Follow The Scientist

icon-facebook icon-linkedin icon-twitter icon-vimeo icon-youtube
Advertisement
Mettler Toledo
Mettler Toledo

Stay Connected with The Scientist

  • icon-facebook The Scientist Magazine
  • icon-facebook The Scientist Careers
  • icon-facebook Neuroscience Research Techniques
  • icon-facebook Genetic Research Techniques
  • icon-facebook Cell Culture Techniques
  • icon-facebook Microbiology and Immunology
  • icon-facebook Cancer Research and Technology
  • icon-facebook Stem Cell and Regenerative Science
Advertisement
Mettler Toledo
Mettler Toledo
Advertisement
The Scientist
The Scientist
Life Technologies