Advertisement

News & Opinion

Covering the life sciences inside and out

Most Recent

NEW YORK, July 19 (Praxis Press) Using serum cholesterol levels to predict coronary heart disease (CHD) and whether to treat hypercholesterolemia in people under the age of 40 is controversial. To evaluate the long-term impact of unfavorable serum cholesterol levels on risk of death from CHD, cardiovascular disease (CVD), and all causes, Stamler and colleagues evaluated a total of 11,017 men aged 18 through 39 years from three large prospective studies (see paper). The researchers measured cause

0 Comments

Colon-cancer screening

July 21, 2000

NEW YORK, July 20 (Praxis Press) Whether or not colonoscopy is useful in screening asymptomatic adults for colorectal cancer is unclear. To determine the prevalence and risk of colonic neoplasia in asymptomatic patients, Lieberman and colleagues performed colonoscopy on 3 121 patients at 13 Veterans Affairs medical centers (see paper). Examination detected one or more neoplastic lesions in 37.5% of the patients, an adenoma with a diameter of at least 10 mm or a villous adenoma in 7.9%, an adeno

0 Comments

COX-2 and renal function

July 21, 2000

NEW YORK, July 18 (Praxis Press) A new class of nonsteroidal anti-inflammatory drugs selectively inhibits cyclooxygenase (COX)-2 and may produce fewer adverse effects than nonselective inhibitors. However, animal studies suggest that COX-2 is important for normal renal function. Swan and colleagues conducted a randomized, controlled trial of varied doses of rofecoxib (a selective COX-2 inhibitor at therapeutic doses), indomethacin (a COX-1 and COX-2 inhibitor), and placebo in elderly people on a

0 Comments

NEW YORK, July 20 (Praxis Press) The association between distal colorectal polyps and advanced proximal neoplasia is uncertain. Imperiale and colleagues determined the risk of advanced proximal neoplasia among persons with distal hyperplastic or neoplastic polyps and compared the findings to those of persons with no distal polyps. To perform the study the researchers analyzed data from 1 994 asymptomatic adults who underwent colonoscopy for the first time. Of the subjects, 3.1% had advanced lesi

0 Comments

NEW YORK, July 17 (Praxis Press) Familial hypercholesterolemia is an inherited condition characterized by high cholesterol levels and an increased risk of heart disease. About 1 in 500 people are affected by this condition and could benefit from cholesterol-lowering drugs. However, a recent study (see paper) found that only one quarter of affected people were being diagnosed, and children and young adults were most likely to be underdiagnosed. When a family has a history of heart disease at a yo

0 Comments

G8 summit will discuss tropical diseases

By | July 21, 2000

Japan is promising to boost its support for work in HIV/AIDS and parasitic tropical diseases.

0 Comments

NEW YORK, July 17 (Praxis Press) Studies suggest that cardiomyocytes undergo apoptosis after myocardial infarction (MI), and characterization of the extent and timeline of this phenomenon might help tailor new therapeutic interventions. Hofstra and colleagues studied the uptake of technetium-99m-labelled annexin-V in the myocardium of patients with acute MI (see paper). In six of seven patients, labeled annexin-V was taken up by the infarct area only, and this area corresponded to a perfusion de

0 Comments

NEW YORK, July 17 (Praxis Press) Magnetic resonance cholangiopancreatography (MRCP) is a promising alternative to endoscopic retrograde cholangiopancreatography (ERCP), but its accuracy has not been proven in a large controlled study. Adamek and colleagues prospectively compared MRCP and ERCP for the differentiation of pancreatic lesions in 124 patients with suspected pancreatic cancer (see paper). For the diagnosis of pancreatic cancer, MRCP had a sensitivity of 84% and a specificity of 97%, wh

0 Comments

Prophylactic mastectomy

July 21, 2000

NEW YORK, July 19 (Praxis Press) Prophylactic mastectomy is a preventive option for women who wish to reduce their risk of breast cancer but the psychological and social consequences of this procedure is unclear. To evaluate patients' long-term satisfaction and psychological and social function following prophylactic mastectomy, Frost and colleagues surveyed 572 women undergoing bilateral prophylactic mastectomy (see paper). The questionnaire was designed to evaluate satisfaction with the proced

0 Comments

Sprue and T cells

July 21, 2000

NEW YORK, July 17 (Praxis Press) The cellular abnormalities and long-term prognosis of refractory sprue are largely unknown. Cellier and colleagues studied the phenotypic and molecular features of intraepithelial T cells in patients with refractory sprue (see paper). Analysis of intestinal tissue revealed an aberrant intraepithelial lymphoid population and T-cell receptor gene rearrangements in most patients. Patients with aberrant lymphocytes had a poorer prognosis, and some developed overt T-c

0 Comments

Follow The Scientist

icon-facebook icon-linkedin icon-twitter icon-vimeo icon-youtube
Advertisement

Stay Connected with The Scientist

  • icon-facebook The Scientist Magazine
  • icon-facebook The Scientist Careers
  • icon-facebook Neuroscience Research Techniques
  • icon-facebook Genetic Research Techniques
  • icon-facebook Cell Culture Techniques
  • icon-facebook Microbiology and Immunology
  • icon-facebook Cancer Research and Technology
  • icon-facebook Stem Cell and Regenerative Science
Advertisement
ProteinSimple
ProteinSimple
Advertisement
NeuroScientistNews
NeuroScientistNews
Life Technologies