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Coloured cotton, a giant carp, Bt-resistant poplars - is anything holding Chinese biotechnology back? Yes, says Zhao Zhizen - a government that won't take any risks.

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Colposcopy guidelines

June 26, 2000

NEW YORK, June 26 (Praxis Press) Currently no guidelines exist for managing women with low grade cytological abnormalities, whose findings on colposcopy do not warrant immediate treatment. To develop an evidence-based protocol for these women, Teale and colleagues evaluated 566 women with low-grade cytological abnormalities who were not treated at a first visit to the colposcopy clinic, and followed them for a total of 881 years (see paper). Abnormalities resolved in 306 (54.1%) women, whereas 1

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NEW YORK, June 26 (Praxis Press) Type 2 diabetes mellitus is a common complication of iron-overload diseases such as hereditary hemochromatosis. Recently a gene mutation was identified that strongly predisposes individuals towards hemochromatosis when present in homozygous form. Salonen and colleagues examined whether a carrier status for the mutation predicts the development of type 2 diabetes (see paper). Out of a total of 555 participants, one was homozygous and 34 heterozygous for the HFE C2

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Consider quantifying levels of HPV DNA in women at high risk of cervical cancer.

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Consider follow-up measurement of cardiac troponin T is patients with chest pain.

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What's behind today's announcement of the first draft of the genome.

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Statins and osteoporosis

June 26, 2000

NEW YORK, June 26 (Praxis Press) Experimental evidence has shown that the cholesterol-lowering statin drugs may increase bone formation. Chan and colleagues undertook a population-based case-control study at six health-maintenance organizations in the USA to investigate the relationship between statin use and fracture risk among older women. They selected 928 women over 60 years of age who had non-pathological fracture of the hip, humerus, distal tibia, wrist, or vertebrae and compared their sta

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Stomach cancer risk

June 26, 2000

NEW YORK, June 26 (Praxis Press) Stomach cancer is thought to result from Helicobacter pylori infection, most common where socioeconomic conditions are poor. Leon and colleagues have found that mortality from stomach cancer among 65-74 year old men correlates with infant mortality in 27 countries and that the two factors are strongly related (see editorial, or paper). To perform the analysis the researchers obtained death rates from stomach cancer and other causes from a database of the World He

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Acute chest syndrome

June 23, 2000

NEW YORK, June 23 (Praxis Press) Acute chest syndrome is the leading cause of death among patients with sickle cell disease, but its cause is largely unknown. To determine the cause of acute chest syndrome and its response to therapy, Vichinsky and colleagues performed a study of 671 episodes of the acute chest syndrome in 538 patients with sickle cell disease. They found that among patients with sickle cell disease, acute chest syndrome is commonly precipitated by fat embolism and infection, es

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"African levels" of ill-health push the US health system to 37th rank

By | June 22, 2000

The World Health Organisation (WHO)'s World Health Report for the year 2000 faces health ministries head on, and refuses to take their data for granted. Instead, it makes its own statistical analysis of how well 191 different national health systems are functioning. Tables cover a wide range of indicators, but summing up performance into a single measure, the report ranks the massively costly US system way down the list.WHO's Chris Murray

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