Proteins with unstable 3-D structures help the microscopic animals withstand drying.
June 5, 2001|
A recent report linked the human NOTCH4 locus with susceptibility to schizophrenia. In the June issue of Nature Genetics, two reports cast doubt on the NOTCH4-schizophrenia association. Sklar et al. conducted a large-scale study involving 519 parent-offspring trios in three independent families (compared to 80 trios in the original linkage study; Nature Genetics 2001, 28:126-128). Extensive association analyses failed to confirm the previous linkage results. McGinnis et al. analysed (CTG)n and