As the climate warms, moss growth dramatically spreads on the continent’s peninsula.
July 4, 2001|
The gene-trap strategy can exploit insertional mutagenesis to allow phenotypic screening. In the July issue of Nature Genetics, Mitchell et al. demonstrate the power of gene-trap mutagenesis for genome-wide analysis of the genes involved in mouse development (Nature Genetics 2001, 298:241-24). Their modified 'secretory-trap' vector selects genes that have secretory signal sequences or transmembrane domains. Screening over 500 insertions in mouse embryonic stem (ES) cells identified 187 individua