Stress-related genes may be preferentially and rhythmically expressed as part of the circadian rhythms of older fruit flies, researchers report.
May 14, 2001|
Linkage disequilibrium (LD) refers to the correlation among neighboring alleles, reflecting common haplotype ancestry. In the May 10 Nature, Reich et al. describe a systematic, genome-wide analysis of LD within human populations (Nature 2001, 411:199-204). They analyzed 19 random chromosomal regions, each of which centers around a core SNP (single length polymorphism) in the coding region of a gene. Extensive sequencing of 44 individuals from Utah identified 272 'high frequency' SNPs at 0-160 ki