Academic research could be strengthened by thinking more and doing less.
September 26, 2000
Historically, influenza outbreaks have been tracked by clinical findings and serology, and characterized by culture. In a study published in the latest issue of the British Medical Journal, Carman and colleagues compared the relative speed and sensitivity of three flu surveillance assays: serology, culture and polymerase chain reaction (PCR). Samples were collected from the nose and throat of 168 patients within a mean 5.3 days after the onset of flu symptoms; 112 patients were subsequently con