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An analysis of human cancer genome projects uncovers a counterintuitive loss of ribosomal gene copies.

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A study suggests that “chief” cells in the stomach act as reserve stem cells that are activated by tissue damage and may be the long-sought source of gastric cancer.

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image: Was a Drop in CRISPR Firms’ Stock Warranted?

Was a Drop in CRISPR Firms’ Stock Warranted?

By | June 7, 2017

A study of off-target effects that sparked fear among investors of genome-editing companies receives methodological criticisms.

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image: Bacterial Photography Goes Technicolor

Bacterial Photography Goes Technicolor

By | May 22, 2017

Genetically engineered "disco bacteria" sense and respond to different colors of light, creating both stunning art in the culture dish and new possibilities for synthetic biology.

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image: Blood Stem Cells Grown in the Lab

Blood Stem Cells Grown in the Lab

By | May 17, 2017

Researchers identify transcription factors and environmental conditions necessary to reprogram human and mouse cells into cells that function like hematopoietic stem cells.

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image: Quick and Cheap Zika Detection

Quick and Cheap Zika Detection

By | May 3, 2017

A heat block, a truck battery, and a novel RNA amplification assay make for in-the-field surveillance of the virus.

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By implanting patient- or rodent-derived mini-guts into mice, scientists can rapidly create more-accurate murine models of the disease

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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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image: Abundant Sequence Errors in Public Databases

Abundant Sequence Errors in Public Databases

By | February 16, 2017

A new algorithm reveals hoards of preparation-induced DNA mutations in publicly available human sequences.

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image: Broad Wins CRISPR Patent Interference Case

Broad Wins CRISPR Patent Interference Case

By | February 15, 2017

The USPTO’s Patent Trial and Appeal Board has ruled in favor of the Broad Institute of MIT and Harvard retaining intellectual property rights covered by its patents for CRISPR gene-editing technology.

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