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image: Personalized Cancer Vaccines

Personalized Cancer Vaccines

By | April 2, 2015

A dendritic cell vaccine targeting melanoma patients’ tumor-specific mutations can activate a broad range of cancer-fighting T cells. 


image: Enzyme Improves CRISPR

Enzyme Improves CRISPR

By | April 1, 2015

A smaller Cas9 protein enables in vivo genome engineering via viral vectors.


image: Opinion: Upgrading Cancer Prevention

Opinion: Upgrading Cancer Prevention

By | April 1, 2015

Preemptive detection and intervention will be key to easing the growing burden of cancer, particularly in developing countries.

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image: Opinion: Making Cancer Vaccines Work

Opinion: Making Cancer Vaccines Work

By | March 31, 2015

Armed with the right adjuvant system, vaccines are poised to tackle one of the world’s most intractable diseases. 


image: Stimulating Neurons with Light and Gold

Stimulating Neurons with Light and Gold

By | March 12, 2015

Researchers develop a technique to trigger neural activity in culture using light to heat gold nanoparticles.


image: Engineered Biomarkers Could ID Cancer Cells

Engineered Biomarkers Could ID Cancer Cells

By | February 23, 2015

Scientists develop synthetic blood-based biomarkers to amplify tumor signals in a mouse model.


image: Exploring the Epigenome

Exploring the Epigenome

By | February 18, 2015

A National Institutes of Health-funded consortium publishes 111 reference maps of DNA and histone marks.


image: Culturing Changes Cells

Culturing Changes Cells

By | February 3, 2015

Within days of their transfer to a dish, a certain epigenetic mark vanishes from mouse cells.


image: Benefits of Missing MYC

Benefits of Missing MYC

By | January 22, 2015

Mice engineered to have just one copy of the gene Myc live longer, healthier lives than wild-type animals.

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image: Stem Cell Divisions Help Explain Cancer Risk

Stem Cell Divisions Help Explain Cancer Risk

By | January 1, 2015

An analysis of 31 tissues finds that random mutations acquired during stem cell divisions correlate with lifetime cancer risk—more so than heritable mutations and environmental factors combined.  


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